aztreonam brands

2 registered brands containing aztreonam in South Africa.

Aztreonam 2D chemical structure

2D structure

Aztreonam

PubChem CID 5742832

Molecular formula: C13H17N5O8S2

The bactericidal action of aztreonam results from the inhibition of bacterial cell wall synthesis due to a high affinity of aztreonam for penicillin binding protein 3 (PBP3). By binding to PBP3, aztreonam inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that aztreonam interferes with an autolysin inhibitor.

Source: PubChem (NCBI) ยท compound 5742832

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Product Manufacturer Status Country
AZTREONAM AVIBACTAM 1,5 g/0,5 g PFIZER - Registered South Africa
EMBLAVEO 1,5 g/0,5 g - Registered South Africa