cefepime brands

3 registered brands containing cefepime in Zambia.

Molecular formula: C19H24N6O5S2

Cefepime is a bactericidal cephalosporin with a mode of action similar to other beta-lactam antibiotics. Cefepime disrupts bacterial cell walls by binding and inhibiting transpeptidases known as penicillin-binding proteins (PBPs), which are enzymes involved in the final stages of peptidoglycan layer synthesis. This results in the lysis and death of susceptible microorganisms. Cefepime has a broad spectrum of _in vitro_ activity that includes both Gram-positive and Gram-negative bacteria. Cefepime has affinity for PBP-3 and PBP-1 in _Escherichia coli_ and _Pseudomonas aeruginosa_, as well as PBP-2 in _E. coli_ and _Enterobacter cloacae_.

Source: PubChem (NCBI) ยท compound 5479537

Product Manufacturer Status Country
Cefepime
Powder for Injection/infusion
Pharco B Registered/Compliant Zambia
IVIPIME
Dry powder for injection
Vhb Medi Sciences Registered/Compliant Zambia
Necpime 1G injection
Powder for Injection
Nectar Lifesciences Registered/Compliant Zambia