cefepime brands
3 registered brands containing cefepime in Zambia.
Cefepime
PubChem CID 5479537Molecular formula: C19H24N6O5S2
Cefepime is a bactericidal cephalosporin with a mode of action similar to other beta-lactam antibiotics. Cefepime disrupts bacterial cell walls by binding and inhibiting transpeptidases known as penicillin-binding proteins (PBPs), which are enzymes involved in the final stages of peptidoglycan layer synthesis. This results in the lysis and death of susceptible microorganisms. Cefepime has a broad spectrum of _in vitro_ activity that includes both Gram-positive and Gram-negative bacteria. Cefepime has affinity for PBP-3 and PBP-1 in _Escherichia coli_ and _Pseudomonas aeruginosa_, as well as PBP-2 in _E. coli_ and _Enterobacter cloacae_.
Source: PubChem (NCBI) ยท compound 5479537
| Product | Manufacturer | Status | Country |
|---|---|---|---|
| Cefepime Powder for Injection/infusion |
Pharco B | Registered/Compliant | Zambia |
| IVIPIME Dry powder for injection |
Vhb Medi Sciences | Registered/Compliant | Zambia |
| Necpime 1G injection Powder for Injection |
Nectar Lifesciences | Registered/Compliant | Zambia |