menthol brands

129 registered brands containing menthol in Kenya.

menthol

Molecular formula: C10H20O

Exposure to low temperatures often causes allergic responses or urticaria. Similarly, menthol, a common food additive is also known to cause urticaria, asthma, and rhinitis. However, despite the obvious clinical implications, the molecular mechanisms responsible for inducing allergic responses to low temperatures and menthol have not been determined. Because a non-selective cation channel, transient receptor potential subtype M8 (TRPM8) is activated by cold and menthol, we hypothesized that this channel mediates cold- and menthol-induced histamine release in mast cells. Here, we report that TRPM8 is expressed in the basophilic leukemia mast cell line, RBL-2H3, and that exposure to menthol or low temperatures induced Ca(2+) influx in RBL-2H3 cells, which was reversed by a TRPM8 blocker. Furthermore, menthol, a TRPM8 agonist, induced the dose-dependent release of histamine from RBL-2H3 cells. When TRPM8 transcripts were reduced by siRNA (small interfering RNA), menthol- and cold-induced Ca(2+) influx and histamine release were significantly reduced. In addition, subcutaneous injection of menthol evoked scratching, a typical histamine-induced response which was reversed by a TRPM8 blocker. Thus, our findings indicate that TRPM8 mediates the menthol- and cold-induced allergic responses of mast cells, and suggest that TRPM8 antagonists be viewed as potential treatments for cold- and menthol-induced allergies. /DL-Menthol/ Menthol's characteristic cooling sensation is due, in part, to the activation of sensory neurons generally termed transient receptor potential (TRP) channels, in particular transient receptor potential melastatin family member 8 (TRPM8) and transient receptor potential subfamily A, member 1 (TRPA1). Menthol acts upon TRPM8 receptors by rapidly increasing intracellular calcium and mobilizing calcium flux through the channels to induce cold response signals at the application site. Aside from its cold-inducing sensation capabilities, menthol exhibits cytotoxic effects in cancer cells, induces reduction in malignant cell growth, and engages in synergistic excitation of GABA receptors and sodium ion channels resulting in analgesia. /DL-Menthol/ In recent years, the transient receptor potential melastatin member 8 (TRPM8) channel has emerged as a promising prognostic marker and putative therapeutic target in prostate cancer. We have found that forced overexpression of TRPM8 in PC-3 cells can inhibit the cell proliferation and motility probably through the TRPM8 activation. In this study, we aimed to investigate whether activating the TRPM8 channel by its selective agonist menthol can inhibit the proliferation and motility of androgen-independent prostate cancer (AIPC) with remarkable expression of TRPM8. Menthol is a naturally occurring compound, which has been widely used in cosmetics and pharmaceutical products, and also as flavoring in food. DU145 cells are androgen-independent but have a remarkable expression of TRPM8. The demonstration of the existence of TRPM8 and the absence of TRPA1 in DU145 cells provided the foundation for the following experiments, because both TRPM8 and TRPA1 are molecular targets of menthol. The outcome of MTT assay indicated that menthol inhibited the cell growth (p < 0.01). Cell cycle distribution and scratch assay analysis revealed that menthol induced cell cycle arrest at the G(0)/G(1) phase (p < 0.01). Furthermore, menthol inhibited the migration of DU145 cells by downregulating the focal-adhesion kinase. So it suggests that the activation of the existing TRPM8 channels may serve as a potential and pragmatic treatment for those AIPC with remarkable expression of TRPM8, and menthol is a useful compound for future development as an anticancer agent. /DL-Menthol/

Source: PubChem (NCBI) · compound 1254

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Product	Manufacturer	Status	Country
FLEXIMUV PAIN RELIEVER TUPENTINE OIL10%W/W,WINTERGREEN 8%W/W,CAMPHOR 5%W/W,MENTHOL 2%W/W,CAPSICUM 0.4%W/W	Cadila Pharmaceuticals	Registered	Kenya
GO GEL 1.16%/ 10%/ 5% W/W	Unisel	Registered	Kenya
GO GEL 1.16%/ 10%/ 5% W/W	Unisel	Registered	Kenya
GOOD MORNING COUGH TABLETS EACH TABLET CONTAINS TOLU SOLUTION 0.04ML, LIQUORICE 56.35MG, CREOSOTE 2.20MG, CAPSICUM 0.03ML, MENTHOL 11.25ML, ANISE 1.10MG, PEPPERMINT 1.10MG AND EUCALYPTUS 2.20MG	Beta Healthcare	Registered	Kenya
IMACOFF DRY EACH 5MLS CONTAIN DIPHENHYDRAMINE HCL BP-14MG, DEXTROMETHORPAN HBR BP-5.7MG, SODIUM CITRATE BP -57MG AND MENTHOL BP-1.1MG	Daima Dispensing Chemist	Registered	Kenya
IMACOFF EXPECTORANT DIPHENHYDRAMINE HCL BP 14MG, GUAIPHENESIN 100MG AND MENTHOL BP 1.1MG	Daima Dispensing Chemist	Registered	Kenya
IMACOFF PAEDIATRIC EACH 5.0ML CONTAINS: DIPHENHYDRAMINE HCL BP-7MG, SODIUM CITRATE BP -28.5MG AND MENTHOL BP-0.55MG	Daima Dispensing Chemist	Registered	Kenya
ISODEX DRY SYRUP 10MG, 5MG, 1.5MG	Medcure Healthcare	Registered	Kenya
JOINTY PLUS GEL COMPOSITION: LINSEED OIL (OLEUM LINI) BP 3.00 %W/W, DICLOFENAC DIETHYLAMINE BP 1.16 %W/W EQ. TO DICLOFENAC SODIUM 1.00 %W/W, METHYL SALICYLATE BP 10.00 %W/W, MENTHOL BP 5.00 %W/W	Nextgen Pharmaceuticals	Registered	Kenya
KALUMA BALM MENTHOL (MENTHA PIPERITA) 15 % W/W OIL GAULTHERIA (WINTERGREEN OIL) 15 % W/W	Shalina Healthcare	Registered	Kenya
KALUMA GEL WINTERGREEN OIL 15%, MENTHOL 5%, TURPENTINE OIL 3%, EUCALYPTUS OIL 2%, LINSEED OIL 3%, BENZYL ALCOHOL 1%	Shalina Healthcare	Registered	Kenya
KALUMA INHALER MENTHOL (MENTHA PIPERITA): 42.5 W/W %, CAMPHOR (CINNAMOMUM CAMPHORA): 40 W/W %, WINTERGREEN OIL (GAULTHERIA PROCUMBENS) :12.5 W/W %, TURPENTINE OIL (PINUS ROXUBURGHII): 5.0 W/W %	Shalina Healthcare	Registered	Kenya
KALUMA KING LOZENGES MENTHOL (MENTHA PIPERITA) 0.34%W/W EUCALYPTUS OIL (EUCALYPTUS GLOBULUS) 0.24%W/W	Shalina Healthcare	Registered	Kenya
KALUMA SPRAY WINTERGREEN OIL 15%W/W, MENTHOL 5%W/W, TURPENTINE OIL 3%W/W, EUCALYPTUS OIL 2%W/W, CINNAMON OIL 0.4%W/W	Shalina Healthcare	Registered	Kenya
KALUMACOF TABLETS MENTHOL (MENTHA PIPERITA) 10MG ANISE OIL(PIMPINELLA ANISUM) 0.001ML MINT OIL (MENTHA PIPERATTA) 0.001ML EUCALYPTUS OIL (EUCALYPTUS GLOBULUS) 0.002 ML VIBHITAKA (TERMINALIA BELLIRICA) 20 MG CLOVE OIL (SYZYGIUM AROMATICUM) 2.3 ML KATTHA (ACACIA CATECHU) 40	Orange Pharma	Registered	Kenya
KOFAREST SYRUP SALBUTAMOL SULPHATE BP EQUIVALENT TO SALBUTAMOL..2 MG AMBROXOL HYDROCHLORIDE BP.. 30 MG GUAIFENESIN BP..100 MG MENTHOL BP..5 MG	Sai Pharmaceuticals	Registered	Kenya
KOFGON DIPHENHYDRAMINE HYDROCHLORIDE 5MG, CHLORPHENIRAMINE MALEATE 2MG, AMMONIUM CHLORIDE 50MG, SODIUM CITRATE 30MG, MENTHOL 0.25MG	Zain Pharma	Registered	Kenya
KOFORIL TERBUTALINE 1.25MG, BROMHEXINE 2MG, GUAIPHENESIN 50MG AND MENTHOL 0.5MG	Crown Healthcare	Registered	Kenya
LETZGO GEL ETORICOXIB 1% W/W, LINSEED OIL BP 3%W/W, METHYL SALICYLATE BP 10% W/W, MENTHOL BP 5% W/W (PRESERVATIVE: BENZYL ALCOHOL BP 1%W/W)	Simba Pharmaceuticals	Registered	Kenya
LOFNAC GEL EACH GM CONTAINS: LINSEED OIL BP 3% W/W DICLOFENAC DIETHYLAMINE (EQUIVALENT TO DICLOFENAC SODIUM 1% W/W) BP 1.16 W/W METHYL SALICYLATE BP 10% W/W MENTHOL BP 5% W/W PRESERVATIVE BENAYL ALCOHOL BP 1%W/W GEL BASE	Theralife Pharma	Registered	Kenya
LUNAHIST EXPECTORANT CHLORPHENIRAMINE MALEATE BP 2 MG/5ML DIPHENHYDRAMINE HCL 5 MG/5ML AMMONIUM CHLORIDE BP 50MG/5ML SODIUM CITRATE BP 30MG/5ML MENTHOL BP 0.25 MG/5ML	Laboratory & Allied	Registered	Kenya
LYSODOL GEL - ACECLOFENAC BP 1.5% W/W -OLEUM LINI (CONTAINING PREDOMINANTLY ALPHA LINOLENIC ACID) 3% W/W - METHYL SALICYLATE BP 10 % W/W - CAPSAICIN USP 0.01% W/W - MENTHOL USP 5 % W/W	Galaxy Pharmaceutical	Registered	Kenya
LYSOFLAM GEL DICLOFENAC DIETHYLAMINE BP 1.116% W/W METHYL SALICYLATE USP 12.0% W/W MENTHOL USP 5.0% W/W	Phillips Therapeutics	Registered	Kenya
MENTHOLATUM BALM METHYL SALICYLATE 0.33%W/W MENTHOL 1.35%W/W CAMPHOR 9.0%W/W	Harleys	Registered	Kenya
MINFEN GEL DICLOFENAC SODIUM 1%W/W, LINSEED OIL 3% W/W, METHYL SALICYLATE 10%W/W, MENTHOL 2% W/W AND BENZYL ALCOHOL 1% W/W	Zengenta Pharmaceuticals	Registered	Kenya
MUCO-ASTHALIN SYRUP EACH 5ML CONTAINS SALBUTAMOL SULPHATE BP EQUIVALENT TO SALBUTAMOL 2MG, BROMHEXINE HYDROCHLORIDE BP 4MG AND MENTHOL BP 1MG	Beta Healthcare	Registered	Kenya
MUCOCOF SYRUP DIPHENHYDRAMINE HCL B.P. 10MG , AMMONIUM CHLORIDE B.P. 90MG, SODIUM CITRATE B.P. 40MG , CODEINE PHOSPHATE B.P. AND MENTHOL B.P. 9MG	Signature Healthcare	Registered	Kenya
MUCOLEX EXPECTORANT AMBROXOL HYDROCHLORIDE BP 30 MG, SALBUTAMOL SULFATE BP 1MG, GUAIFENESIN BP 50MG, MENTHOL BP 0.5MG.	Unisel	Registered	Kenya
MYOFLAX OLEORESIN CAPSICUM EQ. TO CAPSAICIN 0.075 % W/W, METHYL SALICYLATE BP 20 % W/W, MENTHOL USP 10 % W/W, CAMPHOR USP 5 % W/W, EUCALYPTUS OIL BP 5 % W/W, DICLOFENAC DIETHYLAMINE BP 1.16 % W/W EQ. TO DICLOFENAC SODIUM1 % W/W	Psm Pharmaceuticals	Registered	Kenya
MYOLAXIN-D GEL OLEORESIN CAPSICUM EQUIVALENT TO CAPSAICIN 0.75%W/W, METHYL SALICYLATE BP 20.0%W/W, MENTHOL USP 10.0W/W, CAMPHOR USP 5.0%W/W, EUCALYPTUS OIL BP 5.0%W/W AND DICLOFENAC DIETHYLAMINE BP EQUIVALENT TO DICLOFENAC SODIUM BP 1.0%W/W	Harleys	Registered	Kenya
MYONAC GEL ACECLOFENAC BP 1.5%W/W METHYL SALICYLATE BP 10%W/W VIRGIN LINSEED OIL BP 3%W/W CAPSAICIN USP 0.01%W/W MENTHOL USP 5%W/W	Win-pharma	Registered	Kenya
NATURUB OINTMENT 30G NATURAL CAMPHOR 2.35% EUCALYPTUS OIL BP 1.2% LEMONGRASS OIL EXTRACTS @.47% WINTERGREEN OIL BP 12.7% MENTHOL BP 6.3%	Orange Pharma	Registered	Kenya
NILHEAT GEL LINSEED OIL BP……………………… 3.0 % W/W DICLOFENAC DIETHYL AMMONIUM BP. 1.16 % W/W EQ. TO DICLOFENAC ………………… 1.00 % W/W METHYL SALICYLATE BP……………… 10.0 % W/W MENTHOL BP……………………….. 5.0 % W/W	Nila Pharmaceuticals	Registered	Kenya
NOPEN BALM MENTHOL 2% W/V CAMPHOR 5%W/V METHYL SALICYLATE 6%W/V TURPENTINE OIL 1% W/V EUCALYPTUS OIL 5%W/V CLOVE OIL 0.5%W/V CAPSICUM EXTRACT 0.1%W/V LEMON GRASS OIL 3%W/V.	Laboratory & Allied	Registered	Kenya
OBREX EXPECTORANT CHLORPHENIRAMINE MALEATE2MG/5ML EPHEDRINE HCL 5MG/5MLSODIUM CITRATE 40MG/5ML MENTHOL 0.25MG/5ML	Laboratory & Allied	Registered	Kenya
ONACOF SYRUP EACH 5 ML CONTAINS: SALBUTAMOL SULPHATE BP EQ. TO SALBUTAMOL 1 MG BROMHEXINE HYDROCHLORIDE BP 2 MG GUAIPHENESIN BP 50 MG MENTHOL BP 0.5 MG	Harleys	Registered	Kenya
PANORUB CREAM 10% : 5% : 0.1%	Cosmos	Registered	Kenya
PHILCORIL BM EXPECTORANT 1MG, 2MG, 50MG, 0.5MG	Philmed	Registered	Kenya
PIRITEXYL BR EXPECTORANT AMBROXOL HYDROCHLORIDE 50 MG GUAFENESIN 50 MG TERBUTALINE SULPHATE 1.25 MG & MENTHOL 2.50 MG	Unisel	Registered	Kenya
POWER HEAT METHYL SALICYLATE BP 15.00 % W/W, MENTHOL BP 10.00 % W/W, TURPENTINE OIL BP 2.00 % W/W, EUCALYPTUS OIL BP 2.00 % W/W CAMPHOR BP 3.00 % W/W	Syner-med Pharmaceuticalsltd	Registered	Kenya
POWER HEAT PLUS METHYL SALICYLATE BP 10.00 % W/W, DICLOFENAC DIETHYLAMINE BP 1.16 %W/W EQ. TO DICLOFENAC SODIUM BP 1.00 % W/W ,LINSEED OIL BP 3.00 %,MENTHOL BP 5.00 % W/W & CAPSAICIN USP 0.025 % W/W	Syner-med Pharmaceuticalsltd	Registered	Kenya
POWERGESIC PLUS GEL DICLOFENAC DIETHYLAMINE BP 1.16% W/W EQUIVELANT TO DICLOFENAC SODIUM BP 1% W/W LINSEED OIL BP 3% W/W MENTHOL BP 5% W/W METHYL SALICYLATE BP 10% W/W	Unisel	Registered	Kenya
RESPILLIN BR EXPECTORANT SULBUTAMOL 2MG BROMHEXINE HCL 4MG GUAIFENSIN 100MG MENTHOL 1MG	National Pharmacy	Registered	Kenya
RHOMO OIL RHUS TOXICODENDRON 60LT, BRYONIA ALBA 30LT, TEREBINTHENA OLEUM 60LT, CAMPHOR 60LT, MENTHOL 30LT, THYMOL 30LT, SYMPHYTUM OFFICINALE 30LT	Eastleigh Pharmaceutuical Limited	Registered	Kenya
RUFENAC GEL DICLOFENAC DIETHYL AMMONIUM SALT 1.16%W/W EQUIVALENT TO DICLOFENAC SODIUM BP 1%W/W, METHYL SALICYLATE BP 3% W/W, MENTHOL BP 2% W/W	Shalina Healthcare	Registered	Kenya
SALOREX EXPECTORANT SYRUP BROMHEXINE 2MG, GUAIFENESIN 50MG, MENTHOL 0.5MG , SALBUTAMOL 2MG	Biopharma	Registered	Kenya
SALOREX TABLETS EACH TABLET CONTAINS, SALBUTAMOL SULPHATE EQUIVALENT TO SALBUTAMOL 2MG, BROMHEXINE HCL 4MG, GUAIFENESIN 100MG& MENTHOL 1MG	Biopharma	Registered	Kenya
SHALTOUX 4 WAY RELIEF SYRUP EACH 5 ML CONTAINS: DIPHENHYDRAMINE HYDROCHLORIDE BP 14 MG, AMMONIUM CHLORIDE BP 135 MG , SODIUM CITRATE BP 57 MG, MENTHOL BP 1.1 MG , COLOUR: CARAMEL FLAVOUR: MIX FRUIT, COOLMINT	Shalina Healthcare	Registered	Kenya
SINAREST VAPOCAPS CAMPHOR USP.. 25 MG CHLOROTHYMOL..5MG EUCALYPTOL BPC..125 MG MENTHOL USP..65 MG TERPINEOL BP.. 120 MG	Sai Pharmaceuticals	Registered	Kenya
SONACOF TABLETS MENTHOL (MENTHA PIPERITA) 10MG, CAMPHOR (CINNAMOMUM CAMPHOR 0.15MG), THYMOL (PTYCHOTIS AJOWAN) 0.2MG, EUCALYPTUS OIL (EUCALYPTUS GLOBULES OIL) 2MG	Shalina Healthcare	Registered	Kenya

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