Drug Interactions Database

6278 interactions from BNF 85 - Check your medicines

Source: BNF 85
Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916
letermovir thrombininhibitors

decreases concentration

Severe Theoretical
levodopa linezolid

increases risk of elevatedbloodpressure

Severe Theoretical
levonorgestrel ulipristalandulipristalmightdecreasetheefficacyoflevonorgestrel

decreases efficacy

Severe Theoretical
livevaccines abrocitinib

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines baricitinib

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines dexrazoxane

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines filgotinib

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines ironchelators

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines ozanimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines ponesimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines siponimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
livevaccines upadacitinib

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
lorlatinib alfentanil

decreases exposure

Severe Theoretical
lorlatinib benzodiazepines

decreases exposure

Severe Study
lorlatinib combinedhormonalcontraceptives

decreases exposure

Severe Theoretical
lorlatinib fentanyl

decreases exposure

Severe Theoretical
lorlatinib opioids

decreases exposure

Severe Theoretical
lumacaftor antiepileptics

decreases exposure

Severe Theoretical
lumacaftor benzodiazepines

decreases exposure

Severe Theoretical
lumacaftor carbamazepine

decreases exposure

Severe Theoretical
lumacaftor ciclosporin

decreases exposure

Severe Theoretical
lumacaftor doravirine

decreases exposure

Severe Theoretical
lumacaftor everolimus

decreases exposure

Severe Theoretical
lumacaftor fosphenytoin

decreases exposure

Severe Theoretical
lumacaftor midazolam

decreases exposure

Severe Theoretical
lumacaftor phenobarbital

decreases exposure

Severe Theoretical
lumacaftor phenytoin

decreases exposure

Severe Theoretical
lumacaftor primidone

decreases exposure

Severe Theoretical
lumacaftor tacrolimus

decreases exposure

Severe Theoretical
lumacaftor temsirolimus

decreases exposure

Severe Theoretical
macrolides ergometrine

increases risk of ergotism

Severe Theoretical
macrolides ergotamine

increases risk of ergotism

Severe Theoretical
macrolides fidaxomicin

increases exposure

Severe Study
macrolides irinotecan

increases risk of toxicity

Severe Study
macrolides tepotinib

increases exposure

Severe Theoretical
mao-binhibitors beta

increases risk of severehypertension

Severe Theoretical
mao-binhibitors methylphenidate

increases risk of ahypertensivecrisis

Severe Theoretical
maois,irreversible alphablockers

increases effects

Severe Theoretical
maois,irreversible antihistamines,non-sedating

increases risk of antimuscarinicadverseeffects

Severe Theoretical
maois,irreversible antihistamines,sedating

increases risk of antimuscarinicadverseeffects

Severe Theoretical
maois,irreversible indoramin

increases effects

Severe Theoretical
maraviroc fosamprenavirandfosamprenavirpotentiallydecreasestheexposuretomaraviroc

decreases exposure

Severe Study
mefenamicacid regorafenib

increases exposure

Severe Theoretical
memantine ketamine

increases risk of cnsadverseeffects

Severe Theoretical
mepacrine antimalarials

increases concentration

Severe Theoretical
mepacrine primaquine

increases concentration

Severe Theoretical
methylphenidate apraclonidine

decreases effects

Severe Theoretical
methylphenidate linezolid

increases risk of elevatedbloodpressure

Severe Theoretical
methylthioniniumchloride bupropion

increases risk of severehypertension

Severe Theoretical
metoclopramide antimalarials

decreases concentration

Severe Study
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6278 interactions
Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.