Drug Interactions Database

6278 interactions from BNF 85 - Check your medicines

Source: BNF 85
Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916
mitotane phosphodiesterasetype-

decreases exposure

Severe Study
mitotane piperaquine

decreases concentration

Severe Theoretical
mitotane praziquantel

decreases exposure

Severe Study
mitotane remdesivir

decreases exposure

Severe Theoretical
mitotane ribociclib

decreases exposure

Severe Study
mitotane selpercatinib

decreases exposure

Severe Study
mitotane sirolimus

decreases concentration

Severe Study
mitotane taxanes

decreases exposure

Severe Study
mitotane temsirolimus

decreases concentration

Severe Study
mitotane tepotinib

decreases exposure

Severe Theoretical
mitotane theactive

decreases exposure

Severe Study
mitotane theactivemetaboliteoffostemsavir

decreases exposure

Severe Study
mitotane ticagrelor

decreases exposure

Severe Study
mitotane velpatasvir

decreases exposure

Severe Study
mitotane vinflunine

decreases exposure

Severe Theoretical
mitotane voxilaprevir

decreases concentration

Severe Study
moclobemide clopidogrel

decreases efficacy

Severe Study
moclobemide rizatriptan

increases exposure

Severe Study
moclobemide sumatriptan

increases exposure

Severe Study
moclobemide triptans

increases exposure

Severe Study
modafinil mobocertinib

decreases exposure

Severe Theoretical
modafinil voxilaprevir

decreases concentration

Severe Theoretical
modafinil zanubrutinib

decreases exposure

Severe Theoretical
monoclonalantibodies fingolimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
monoclonalantibodies ozanimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
monoclonalantibodies siponimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical
monoclonalantibodies vemurafenib

increases risk of hepatotoxicity

Severe Study
nevirapine ketoconazole

decreases exposure

Severe Study
nicorandil phosphodiesterasetype-

increases risk of hypotension

Severe Theoretical
nilotinib antipsychotics,secondgeneration

increases exposure

Severe Study
nirmatrelvirboostedwithritonavir antifungals,azoles

decreases concentration

Severe Theoretical
nirmatrelvirboostedwithritonavir voriconazole

decreases concentration

Severe Theoretical
nitrates prilocaine

increases risk of methaemoglobinaemia

Severe Theoretical
nitrates topicalanaesthetics,local

increases risk of methaemoglobinaemia

Severe Theoretical
nitrousoxide methotrexate

increases risk of methotrexatetoxicity

Severe Study
nnrtis abrocitinib

decreases exposure

Severe Theoretical
nnrtis avapritinib

decreases exposure

Severe Theoretical
nnrtis bedaquiline

decreases exposure

Severe Theoretical
nnrtis bosutinib

decreases exposure

Severe Theoretical
nnrtis diazepam

increases exposure

Severe Theoretical
nnrtis elbasvir

decreases exposure

Severe Theoretical
nnrtis grazoprevir

decreases exposure

Severe Theoretical
nnrtis mobocertinib

decreases exposure

Severe Theoretical
nnrtis relugolix

decreases exposure

Severe Study
nnrtis zanubrutinib

decreases exposure

Severe Theoretical
norethisterone ulipristalandulipristalmightdecreasetheefficacyofnorethisterone

decreases efficacy

Severe Theoretical
normalimmunoglobulin dinutuximab

affects effects

Severe Theoretical
normalimmunoglobulin monoclonalantibodies

affects effects

Severe Theoretical
nsaids mifamurtide

decreases efficacy

Severe Theoretical
opicapone meglitinides

increases exposure

Severe Study
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6278 interactions
Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.