Drug Interactions Database

1418 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

fluorouracil phenytoin

increases concentration

Moderate Anecdotal

fluoxetine selumetinib

increases exposure

Moderate Theoretical

fluvoxamine alprazolam

increases exposure

Moderate Study

fluvoxamine amitriptyline

increases exposure

Moderate Study

fluvoxamine antiarrhythmics

increases exposure

Moderate Study

fluvoxamine antipsychotics,secondgeneration

increases concentration

Moderate Study

fluvoxamine benzodiazepines

increases exposure

Moderate Study

fluvoxamine cinacalcet

increases exposure

Moderate Theoretical

fluvoxamine clomipramine

increases exposure

Moderate Study

fluvoxamine clozapine

increases concentration

Moderate Study

fluvoxamine dopaminereceptoragonists

increases exposure

Moderate Study

fluvoxamine erlotinib

increases exposure

Moderate Theoretical

fluvoxamine haloperidol

increases concentration

Moderate Study

fluvoxamine imipramine

increases exposure

Moderate Study

fluvoxamine olanzapine

increases exposure

Moderate Anecdotal

fluvoxamine propafenone

increases exposure

Moderate Study

fluvoxamine ropinirole

increases exposure

Moderate Study

fluvoxamine tricyclicantidepressants

increases exposure

Moderate Study

folates antiepileptics

decreases concentration

Moderate Study

folates fosphenytoin

decreases concentration

Moderate Study

folates phenobarbital

decreases concentration

Moderate Study

folates phenytoin

decreases concentration

Moderate Study

folates primidone

decreases concentration

Moderate Study

fosphenytoin aminophylline

decreases exposure

Moderate Study

fosphenytoin doxycycline

decreases concentration

Moderate Theoretical

fosphenytoin tetracyclines

decreases concentration

Moderate Theoretical

fostamatinib digoxin

increases exposure

Moderate Study

fostamatinib simvastatin

increases exposure

Moderate Study

fostemsavir ethinylestradiolfromacombinedhormonalcontraceptive

increases concentration

Moderate Study

fostemsavir tenofoviralafenamide

increases exposure

Moderate Theoretical

fostemsavir tenofovirh

increases exposure

Moderate Theoretical

gemfibrozil pioglitazone

increases exposure

Moderate Study

gemfibrozil roxadustat

increases exposure

Moderate Study

gemfibrozil treprostinil

increases exposure

Moderate Study

givosiran agomelatine

increases exposure

Moderate Study

givosiran atomoxetine

increases exposure

Moderate Study

givosiran betablockers,selective

increases exposure

Moderate Study

givosiran dopaminereceptoragonists

increases exposure

Moderate Study

givosiran duloxetine

increases exposure

Moderate Study

givosiran eliglustat

increases exposure

Moderate Study

givosiran melatonin

increases exposure

Moderate Study

givosiran nebivolol

increases exposure

Moderate Study

givosiran rasagiline

increases exposure

Moderate Study

givosiran ropinirole

increases exposure

Moderate Study

givosiran tizanidine

increases exposure

Moderate Study

grapefruitjuice antiepilepticse

increases exposure

Moderate Study

grapefruitjuice carbamazepine

increases exposure

Moderate Study

grapefruitjuice fostamatinib

increases exposure

Moderate Theoretical

grapefruitjuice glasdegib

increases exposure

Moderate Theoretical

grapefruitjuice phosphodiesterasetype-

increases exposure

Moderate Study

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1418 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.