Drug Interactions Database

944 interactions from BNF 85 - Check your medicines

Source: BNF 85
Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916
primidone ketoconazole

decreases concentration

Severe Study
primidone posaconazole

decreases concentration

Severe Study
propafenone nebivolol

increases exposure

Severe Theoretical
propylthiouracil metyrapone

decreases effects

Severe Theoretical
pseudoephedrine linezolid

increases risk of elevatedbloodpressure

Severe Study
ranolazine fidaxomicin

increases exposure

Severe Study
rasagiline methylphenidate

increases risk of ahypertensivecrisis

Severe Theoretical
reboxetine linezolid

increases risk of ahypertensivecrisis

Severe Theoretical
reboxetine moclobemide

increases risk of ahypertensivecrisis

Severe Theoretical
retinoids vitamin

increases risk of vitaminatoxicity

Severe Study
ribavirin zidovudine

increases risk of anaemiaand/orleucopenia

Severe Study
ribociclib alfuzosin

increases exposure

Severe Theoretical
ribociclib alphablockers

increases exposure

Severe Theoretical
ribociclib amiodarone

increases exposure

Severe Theoretical
ribociclib antiarrhythmics

increases exposure

Severe Theoretical
ribociclib antipsychotics,secondgeneration

increases exposure

Severe Theoretical
ribociclib benzodiazepines

increases exposure

Severe Study
ribociclib ergotamine

increases exposure

Severe Theoretical
ribociclib phosphodiesterasetype-

increases exposure

Severe Theoretical
ribociclib pimozide

increases exposure

Severe Theoretical
ribociclib quetiapine

increases exposure

Severe Theoretical
ribociclib simvastatin

increases exposure

Severe Theoretical
rifabutin antifungals,azoles

decreases exposure

Severe Theoretical
rifabutin antimalarials

decreases exposure

Severe Study
rifabutin atovaquone

decreases exposure

Severe Study
rifabutin bictegravir

decreases exposure

Severe Study
rifabutin cabazitaxel

decreases exposure

Severe Theoretical
rifabutin isavuconazole

decreases exposure

Severe Theoretical
rifabutin mobocertinib

decreases exposure

Severe Theoretical
rifabutin taxanes

decreases exposure

Severe Theoretical
rifabutin voxilaprevir

decreases concentration

Severe Theoretical
rifampicin abemaciclib

decreases exposure

Severe Study
rifampicin abiraterone

decreases exposure

Severe Study
rifampicin acalabrutinib

decreases exposure

Severe Study
rifampicin anti-androgens

decreases exposure

Severe Study
rifampicin antiarrhythmics

decreases exposure

Severe Study
rifampicin antimalarials

decreases exposure

Severe Study
rifampicin antimalarials

decreases concentration

Severe Theoretical
rifampicin antipsychotics,secondgeneration

decreases exposure

Severe Theoretical
rifampicin artemether

decreases exposure

Severe Study
rifampicin atovaquone

decreases exposure

Severe Study
rifampicin bedaquiline

decreases exposure

Severe Study
rifampicin berotralstat

decreases concentration

Severe Theoretical
rifampicin bosentan

affects exposure

Severe Study
rifampicin cabazitaxel

decreases exposure

Severe Study
rifampicin cariprazine

decreases exposure

Severe Theoretical
rifampicin cobimetinib

decreases exposure

Severe Theoretical
rifampicin crizotinib

decreases exposure

Severe Study
rifampicin dabigatran

decreases exposure

Severe Study
rifampicin darolutamide

decreases exposure

Severe Study
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944 interactions
Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.