Drug Interactions Database

1418 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

isoniazid carbamazepineandcarbamazepineincreasestheriskofhepatotoxicitywhengivenwithisoniazid

increases concentration

Moderate Study

itraconazole anti-androgens

increases exposure

Moderate Study

itraconazole darolutamide

increases exposure

Moderate Study

ivacaftor bictegravir

increases exposure

Moderate Theoretical

ketoconazole anti-androgens

increases exposure

Moderate Theoretical

ketoconazole coumarins

increases anticoagulant effect

Moderate Anecdotal

ketoconazole darolutamide

increases exposure

Moderate Theoretical

ketoconazole warfarin

increases anticoagulant effect

Moderate Anecdotal

lanreotide oralciclosporin

decreases absorption

Moderate Theoretical

lapatinib bictegravir

increases exposure

Moderate Theoretical

lapatinib panobinostat

increases exposure

Moderate Theoretical

lapatinib theactivemetaboliteofirinotecan

increases exposure

Moderate Study

larotrectinib alfentanil

increases exposure

Moderate Theoretical

larotrectinib benzodiazepines

increases exposure

Moderate Study

larotrectinib ergotamine

increases exposure

Moderate Theoretical

larotrectinib fentanyl

increases exposure

Moderate Theoretical

larotrectinib midazolam

increases exposure

Moderate Study

larotrectinib opioids

increases exposure

Moderate Theoretical

larotrectinib pimozide

increases exposure

Moderate Theoretical

larotrectinib sirolimus

increases exposure

Moderate Theoretical

larotrectinib tacrolimus

increases exposure

Moderate Theoretical

ledipasvir digoxin

increases exposure

Moderate Theoretical

leflunomide cladribine

increases exposure

Moderate Theoretical

leflunomide olanzapine

decreases exposure

Moderate Study

leflunomide rosuvastatin

increases exposure

Moderate Study

leflunomide theophylline

decreases exposure

Moderate Study

letermovir alfentanil

increases exposure

Moderate Study

letermovir amlodipine

increases exposure

Moderate Study

letermovir antiarrhythmics

increases exposure

Moderate Study

letermovir bosutinib

increases exposure

Moderate Study

letermovir buprenorphine

increases exposure

Moderate Study

letermovir buspirone

increases exposure

Moderate Study

letermovir calciumchannelblockers

increases exposure

Moderate Study

letermovir ciclosporinandciclosporinincreasestheexposuretoletermovir

increases exposure

Moderate Study

letermovir corticosteroids

increases exposure

Moderate Study

letermovir coumarins

decreases concentration

Moderate Theoretical

letermovir eliglustat

increases exposure

Moderate Study

letermovir everolimus

increases concentration

Moderate Study

letermovir fedratinib

increases exposure

Moderate Study

letermovir felodipine

increases exposure

Moderate Study

letermovir fentanyl

increases exposure

Moderate Study

letermovir fluvastatin

increases exposure

Moderate Theoretical

letermovir ivacaftor

increases exposure

Moderate Study

letermovir lacidipine

increases exposure

Moderate Study

letermovir lercanidipine

increases exposure

Moderate Study

letermovir methylprednisolone

increases exposure

Moderate Study

letermovir midazolam

increases exposure

Moderate Study

letermovir nicardipine

increases exposure

Moderate Study

letermovir nifedipine

increases exposure

Moderate Study

letermovir nimodipine

increases exposure

Moderate Study

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1418 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.