Drug Interactions Database

944 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

rifampicin trabectedin

decreases exposure

Severe Theoretical

rifampicin vandetanib

decreases exposure

Severe Study

rifampicin vemurafenib

decreases exposure

Severe Study

rifampicin vinflunine

decreases exposure

Severe Theoretical

rifampicin vismodegib

decreases exposure

Severe Theoretical

rifampicin volatilehalogenatedanaesthetics

increases risk of nephrotoxicity

Severe Theoretical

rifampicin voxilaprevir

decreases concentration

Severe Study

rifampicin zanubrutinib

decreases exposure

Severe Study

rifampicinvery antifungals,azoles

decreases exposure

Severe Study

rifampicinvery voriconazole

decreases exposure

Severe Study

rifamycins cabazitaxel

decreases exposure

Severe Theoretical

rifamycins elexacaftor

decreases exposure

Severe Theoretical

rifamycins isavuconazole

decreases exposure

Severe Theoretical

rifamycins ledipasvir

decreases exposure

Severe Theoretical

rifamycins mobocertinib

decreases exposure

Severe Theoretical

rifamycins tenofoviralafenamide

decreases exposure

Severe Theoretical

rifamycins tepotinib

decreases exposure

Severe Theoretical

rifamycins tezacaftor

decreases exposure

Severe Theoretical

rifamycinsmoderatelydecreasetheexposureto atovaquoneandatovaquone rifampicin

increases exposure

Severe Study

rifamycinsmoderatelydecreasetheexposureto atovaquoneandatovaquone rifamycins

increases exposure

Severe Study

ritonavir antipsychotics,secondgeneration

affects exposure

Severe Theoretical

ritonavir benzodiazepines

increases exposure

Severe Theoretical

ritonavir clopidogrel

decreases efficacy

Severe Theoretical

ritonavir clozapine

affects exposure

Severe Theoretical

ritonavir dabigatran

increases exposure

Severe Study

ritonavir diazepam

increases exposure

Severe Theoretical

ritonavir flurazepam

increases exposure

Severe Theoretical

ritonavir glecaprevir

increases exposure

Severe Study

ritonavir opioids

increases risk of cnstoxicity

Severe Study

ritonavir pethidine

increases risk of cnstoxicity

Severe Study

ritonavir tepotinib

increases exposure

Severe Theoretical

ritonavir thrombininhibitors

increases exposure

Severe Study

rucaparib tizanidine

increases exposure

Severe Study

selegiline opioids

increases risk of adverseeffects

Severe Anecdotal

selegiline pethidine

increases risk of adverseeffects

Severe Anecdotal

selpercatinib alfentanil

increases exposure

Severe Study

selpercatinib buprenorphine

increases exposure

Severe Study

selpercatinib ergotamine

increases exposure

Severe Study

selpercatinib everolimus

increases exposure

Severe Study

selpercatinib loopdiuretics

increases exposure

Severe Study

selpercatinib meglitinides

increases exposure

Severe Study

selpercatinib montelukast

increases exposure

Severe Study

selpercatinib opioids

increases exposure

Severe Study

selpercatinib paclitaxel

increases exposure

Severe Study

selpercatinib repaglinide

increases exposure

Severe Study

selpercatinib selexipag

increases exposure

Severe Study

selpercatinib sorafenib

increases exposure

Severe Study

selpercatinib taxanes

increases exposure

Severe Study

selpercatinib torasemide

increases exposure

Severe Study

sodiumbicarbonate methenamine

decreases efficacy

Severe Theoretical

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944 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.