Drug Interactions Database

6278 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

aminophylline erythromycin

decreases exposure

Moderate Study

aminophylline macrolides

decreases exposure

Moderate Study

aminosalicylicacid prilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical

aminosalicylicacid topicalanaesthetics,local

increases risk of methaemoglobinaemia

Moderate Theoretical

aminosalicylicacid topicalprilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical

amiodarone atorvastatin

increases exposure

Moderate Theoretical

amiodarone ciclosporin

increases concentration

Moderate Study

amiodarone dabigatran

increases exposure

Moderate Study

amiodarone fentanyl

increases concentration

Moderate Theoretical

amiodarone opioids

increases concentration

Moderate Theoretical

amiodarone statins

increases exposure

Moderate Theoretical

amiodarone sulfonylureas

increases exposure

Moderate Study

amiodarone thrombininhibitors

increases exposure

Moderate Study

amiodarone ticagrelor

increases exposure

Moderate Study

antiarrhythmics(amiodarone,disopyramide,dronedarone, flecainide,lidocaine betablockers,non-selective

increases risk of cardiovascularadverseeffects

Moderate Study

antiarrhythmics(amiodarone,disopyramide,dronedarone, flecainide,lidocaine betablockers,selective

increases risk of cardiovascularadverseeffects

Moderate Study

antiepileptics chenodeoxycholicacid

affects efficacy

Moderate Theoretical

antiepileptics(fosphenytoin,phenobarbital,phenytoin, primidone prilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical

antiepileptics(fosphenytoin,phenobarbital,phenytoin, primidone raltegravir

affects exposure

Moderate Theoretical

antiepileptics(fosphenytoin,phenobarbital,phenytoin, primidone topicalanaesthetics,local

increases risk of methaemoglobinaemia

Moderate Theoretical

antiepileptics(fosphenytoin,phenobarbital,phenytoin, primidone topicalprilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical

antiepilepticsarepredictedto decreasetheexposuretorifamycinsandrifamycins antiepileptics

decreases exposure

Moderate Study

antiepilepticsarepredictedto decreasetheexposuretorifamycinsandrifamycins phenobarbital

decreases exposure

Moderate Study

antiepilepticsarepredictedto decreasetheexposuretorifamycinsandrifamycins primidone

decreases exposure

Moderate Study

antifungals,azoles alfentanil

increases exposure

Moderate Study

antifungals,azoles amlodipine

increases exposure

Moderate Study

antifungals,azoles antiarrhythmics

increases exposure

Moderate Study

antifungals,azoles buprenorphine

increases exposure

Moderate Study

antifungals,azoles buspirone

increases exposure

Moderate Study

antifungals,azoles calciumchannelblockers

increases exposure

Moderate Study

antifungals,azoles everolimus

increases concentration

Moderate Study

antifungals,azoles felodipine

increases exposure

Moderate Study

antifungals,azoles fentanyl

increases exposure

Moderate Study

antifungals,azoles lacidipine

increases exposure

Moderate Study

antifungals,azoles lercanidipine

increases exposure

Moderate Study

antifungals,azoles methylprednisolone

increases exposure

Moderate Study

antifungals,azoles midazolam

increases exposure

Moderate Study

antifungals,azoles nicardipine

increases exposure

Moderate Study

antifungals,azoles nifedipine

increases exposure

Moderate Study

antifungals,azoles nimodipine

increases exposure

Moderate Study

antifungals,azoles opioids

increases exposure

Moderate Study

antifungals,azoles oxycodone

increases exposure

Moderate Study

antifungals,azoles phosphodiesterasetype-

increases exposure

Moderate Study

antifungals,azoles propafenone

increases exposure

Moderate Study

antifungals,azoles sildenafil

increases exposure

Moderate Study

antifungals,azoles temsirolimus

increases concentration

Moderate Theoretical

antifungals,azoles l corticosteroids

increases exposure

Moderate Study

antifungals,azoles l methylprednisolone

increases exposure

Moderate Study

apalutamide amlodipine

decreases exposure

Moderate Study

apalutamide calciumchannelblockers

decreases exposure

Moderate Study

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6278 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.