Drug Interactions Database

1418 interactions from BNF 85 - Check your medicines

Source: BNF 85
Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916
nitrofurantoin prilocaine

increases risk of e methaemoglobinaemia

Moderate Theoretical
nitrofurantoin topicalanaesthetics,local

increases risk of e methaemoglobinaemia

Moderate Theoretical
nitrofurantoin topicalprilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical
nnrtis coumarins

affects concentration

Moderate Theoretical
nnrtis fluvastatin

increases exposure

Moderate Theoretical
nnrtis osimertinib

decreases exposure

Moderate Theoretical
nnrtis simvastatin

decreases exposure

Moderate Theoretical
nnrtis sirolimus

decreases exposure

Moderate Theoretical
nnrtis tacrolimus

decreases exposure

Moderate Theoretical
nnrtis voriconazoleandvoriconazoleincreasestheexposureto

decreases exposure

Moderate Theoretical
nrtis riociguat

increases exposure

Moderate Study
nsaids antiarrhythmics

increases exposure

Moderate Theoretical
nsaids cladribine

increases exposure

Moderate Theoretical
nsaids flecainide

increases exposure

Moderate Theoretical
nsaids pemetrexed

increases exposure

Moderate Theoretical
nsaids propafenone

increases exposure

Moderate Theoretical
opicapone levodopa

increases exposure

Moderate Study
osilodrostat aminophylline

increases exposure

Moderate Theoretical
osilodrostat antipsychotics,secondgeneration

increases concentration

Moderate Study
osilodrostat antipsychotics,secondgeneration

increases exposure

Moderate Anecdotal
osilodrostat clozapine

increases concentration

Moderate Study
osilodrostat dopaminereceptoragonists

increases exposure

Moderate Study
osilodrostat erlotinib

increases exposure

Moderate Study
osilodrostat olanzapine

increases exposure

Moderate Anecdotal
osilodrostat pirfenidone

increases exposure

Moderate Study
osilodrostat ropinirole

increases exposure

Moderate Study
osilodrostat theophylline

increases exposure

Moderate Theoretical
oxcarbazepine guanfacine

decreases concentration

Moderate Theoretical
palbociclib alfentanil

increases exposure

Moderate Theoretical
palbociclib ciclosporin

increases exposure

Moderate Theoretical
palbociclib ergotamine

increases exposure

Moderate Theoretical
palbociclib everolimus

increases exposure

Moderate Theoretical
palbociclib fentanyl

increases exposure

Moderate Theoretical
palbociclib opioids

increases exposure

Moderate Theoretical
palbociclib pimozide

increases exposure

Moderate Theoretical
palbociclib sirolimus

increases exposure

Moderate Theoretical
palbociclib tacrolimus

increases exposure

Moderate Theoretical
panobinostat atomoxetine

increases exposure

Moderate Theoretical
panobinostat betablockers,selective

increases exposure

Moderate Theoretical
panobinostat metoprolol

increases exposure

Moderate Theoretical
panobinostat nebivolol

increases exposure

Moderate Theoretical
paracetamol prilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical
paracetamol topicalanaesthetics,local

increases risk of methaemoglobinaemia

Moderate Theoretical
paracetamol topicalprilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical
paroxetine procyclidine

increases exposure

Moderate Study
pasireotide oralciclosporin

decreases absorption

Moderate Theoretical
pentoxifylline aminophylline

increases concentration

Moderate Theoretical
pentoxifylline theophylline

increases concentration

Moderate Study
phenobarbital aminophylline

decreases exposure

Moderate Theoretical
phenytoin antipsychotics,secondgeneration

decreases exposure

Moderate Study
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1418 interactions
Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.