Drug Interactions Database

1418 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

phenytoin olanzapine

decreases exposure

Moderate Study

pioglitazone antifungals,azoles

decreases exposure

Moderate Theoretical

pioglitazone isavuconazole

decreases exposure

Moderate Theoretical

posaconazole fostamatinib

increases exposure

Moderate Theoretical

posaconazole glasdegib

increases exposure

Moderate Theoretical

posaconazole panobinostat

increases exposure

Moderate Theoretical

posaconazole pralsetinib

increases exposure

Moderate Study

posaconazole retinoids

increases risk of tretinointoxicity

Moderate Theoretical

posaconazole tretinoin

increases risk of tretinointoxicity

Moderate Theoretical

propafenone acebutolol

increases risk of cardiovascularadverseeffects

Moderate Study

propafenone atenolol

increases risk of cardiovascularadverseeffects

Moderate Study

propafenone betablockers,selective

increases risk of cardiovascularadverseeffects

Moderate Study

propafenone betaxolol

increases risk of cardiovascularadverseeffects

Moderate Study

propafenone bisoprolol

increases risk of cardiovascularadverseeffects

Moderate Study

propafenone celiprolol

increases risk of cardiovascularadverseeffects

Moderate Study

propafenone coumarins

increases anticoagulant effect

Moderate Study

propafenone digoxin

increases concentration

Moderate Study

propafenone esmolol

increases risk of cardiovascularadverseeffects

Moderate Study

propafenone propranolol

increases risk of cardiovascularadverseeffects

Moderate Study

quinine digoxin

increases concentration

Moderate Anecdotal

ranolazine bictegravir

increases exposure

Moderate Theoretical

ranolazine dopaminereceptoragonists

increases exposure

Moderate Study

ranolazine panobinostat

increases exposure

Moderate Theoretical

ranolazine pramipexole

increases exposure

Moderate Study

ranolazine ticagrelor

increases exposure

Moderate Study

retinoids vitamin

increases risk of toxicity

Moderate Theoretical

ribociclib alfentanil

increases exposure

Moderate Theoretical

ribociclib ciclosporin

increases exposure

Moderate Theoretical

ribociclib everolimus

increases exposure

Moderate Theoretical

ribociclib fentanyl

increases exposure

Moderate Theoretical

ribociclib opioids

increases exposure

Moderate Theoretical

ribociclib sirolimus

increases exposure

Moderate Theoretical

ribociclib tacrolimus

increases exposure

Moderate Theoretical

rifabutin clarithromycin

decreases concentration

Moderate Study

rifabutin macrolides

decreases concentration

Moderate Study

rifabutin pralsetinib

decreases exposure

Moderate Study

rifampicin alprazolam

decreases exposure

Moderate Theoretical

rifampicin amlodipine

decreases exposure

Moderate Study

rifampicin antiepileptics

decreases exposure

Moderate Study

rifampicin antiepileptics

decreases concentration

Moderate Study

rifampicin antifungals,azoles

decreases exposure

Moderate Study

rifampicin axitinib

decreases exposure

Moderate Study

rifampicin benzodiazepines

decreases exposure

Moderate Theoretical

rifampicin brivaracetam

decreases exposure

Moderate Study

rifampicin budesonide

decreases exposure

Moderate Study

rifampicin buprenorphine

decreases exposure

Moderate Theoretical

rifampicin buspirone

decreases exposure

Moderate Study

rifampicin calciumchannelblockers

decreases exposure

Moderate Study

rifampicin cannabidiol

decreases exposure

Moderate Study

rifampicin cinacalcet

decreases exposure

Moderate Study

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1418 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.