Drug Interactions Database

1418 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

tetracyclines lithium

increases risk of lithiumtoxicity

Moderate Anecdotal

theophylline lithium

decreases concentration

Moderate Anecdotal

thyroidhormones digoxin

affects concentration

Moderate Theoretical

ticagrelor dabigatran

increases exposure

Moderate Study

ticagrelor thrombininhibitors

increases exposure

Moderate Study

tocilizumab alprazolam

decreases exposure

Moderate Theoretical

tocilizumab aminophylline

decreases exposure

Moderate Theoretical

tocilizumab antiepileptics

decreases exposure

Moderate Theoretical

tocilizumab atorvastatin

decreases exposure

Moderate Study

tocilizumab benzodiazepines

decreases exposure

Moderate Theoretical

tocilizumab calciumchannelblockers

decreases exposure

Moderate Theoretical

tocilizumab ciclosporin

decreases exposure

Moderate Theoretical

tocilizumab corticosteroids

decreases exposure

Moderate Theoretical

tocilizumab coumarins

decreases exposure

Moderate Theoretical

tocilizumab dexamethasone

decreases exposure

Moderate Theoretical

tocilizumab diazepam

decreases exposure

Moderate Theoretical

tocilizumab fosphenytoin

decreases exposure

Moderate Theoretical

tocilizumab methylprednisolone

decreases exposure

Moderate Theoretical

tocilizumab midazolam

decreases exposure

Moderate Theoretical

tocilizumab phenytoin

decreases exposure

Moderate Theoretical

tocilizumab simvastatin

decreases exposure

Moderate Study

tocilizumab statins

decreases exposure

Moderate Study

tocilizumab theophylline

decreases exposure

Moderate Theoretical

tocilizumab warfarin

decreases exposure

Moderate Theoretical

tolcapone levodopa

increases exposure

Moderate Study

trimethoprim dopaminereceptoragonists

increases exposure

Moderate Study

trimethoprim pramipexole

increases exposure

Moderate Study

trimethoprim treprostinil

increases exposure

Moderate Theoretical

tucatinib alfentanil

increases exposure

Moderate Theoretical

tucatinib aliskiren

increases exposure

Moderate Theoretical

tucatinib antihistamines,non-sedating

increases exposure

Moderate Theoretical

tucatinib benzodiazepines

increases exposure

Moderate Study

tucatinib buspirone

increases exposure

Moderate Theoretical

tucatinib colchicine

increases exposure

Moderate Theoretical

tucatinib dabigatran

increases exposure

Moderate Theoretical

tucatinib darifenacin

increases exposure

Moderate Theoretical

tucatinib digoxin

increases exposure

Moderate Study

tucatinib docetaxel

increases exposure

Moderate Theoretical

tucatinib edoxaban

increases exposure

Moderate Theoretical

tucatinib everolimus

increases exposure

Moderate Theoretical

tucatinib fexofenadine

increases exposure

Moderate Theoretical

tucatinib ibrutinib

increases exposure

Moderate Theoretical

tucatinib lomitapide

increases exposure

Moderate Theoretical

tucatinib loperamide

increases exposure

Moderate Theoretical

tucatinib midazolam

increases exposure

Moderate Study

tucatinib naloxegol

increases exposure

Moderate Theoretical

tucatinib opioids

increases exposure

Moderate Theoretical

tucatinib paclitaxel

increases exposure

Moderate Theoretical

tucatinib rivaroxaban

increases exposure

Moderate Theoretical

tucatinib simvastatin

increases exposure

Moderate Theoretical

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1418 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.