Drug Interactions Database

1418 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

berotralstat taxanes

increases concentration

Moderate Study

berotralstat temsirolimus

increases exposure

Moderate Study

berotralstat thrombininhibitors

increases concentration

Moderate Study

berotralstat topotecan

increases concentration

Moderate Study

bosentan amlodipine

decreases exposure

Moderate Theoretical

bosentan benzodiazepines

decreases concentration

Moderate Theoretical

bosentan calciumchannelblockers

decreases exposure

Moderate Theoretical

bosentan everolimus

decreases concentration

Moderate Study

bosentan felodipine

decreases exposure

Moderate Theoretical

bosentan guanfacine

decreases concentration

Moderate Theoretical

bosentan lacidipine

decreases exposure

Moderate Theoretical

bosentan lercanidipine

decreases exposure

Moderate Theoretical

bosentan lurasidone

decreases exposure

Moderate Theoretical

bosentan methadone

decreases exposure

Moderate Study

bosentan midazolam

decreases concentration

Moderate Theoretical

bosentan nicardipine

decreases exposure

Moderate Theoretical

bosentan nifedipine

decreases exposure

Moderate Theoretical

bosentan nimodipine

decreases exposure

Moderate Theoretical

bosentan opioids

decreases exposure

Moderate Study

bosentan osimertinib

decreases exposure

Moderate Study

bosentan ripretinib

decreases exposure

Moderate Theoretical

bosentan ruxolitinib

decreases exposure

Moderate Study

bupropion anticholinesterases,centrallyacting

increases exposure

Moderate Study

bupropion atomoxetine

increases exposure

Moderate Study

bupropion eliglustat

increases exposure

Moderate Study

bupropion fesoterodine

increases exposure

Moderate Theoretical

bupropion galantamine

increases exposure

Moderate Study

bupropion pitolisant

increases exposure

Moderate Study

bupropion risperidone

increases exposure

Moderate Study

bupropion tricyclicantidepressants

increases exposure

Moderate Study

bupropion vortioxetine

increases exposure

Moderate Study

calciumchannelblockers bictegravir

increases exposure

Moderate Theoretical

calciumchannelblockers cladribine

increases exposure

Moderate Theoretical

calciumchannelblockers fentanyl

increases exposure

Moderate Theoretical

calciumchannelblockers fostamatinib

increases exposure

Moderate Theoretical

calciumchannelblockers panobinostat

increases exposure

Moderate Theoretical

calciumchannelblockersincreasetheconcentration ofcarbamazepineandcarbamazepine calciumchannelblockers

decreases exposure

Moderate Anecdotal

calciumchannelblockersincreasetheconcentration ofcarbamazepineandcarbamazepine diltiazem

decreases exposure

Moderate Anecdotal

cannabidiol ciclosporin

increases concentration

Moderate Theoretical

cannabidiol clobazam

increases exposure

Moderate Study

cannabidiol everolimus

increases exposure

Moderate Study

cannabidiol tacrolimus

increases concentration

Moderate Theoretical

cannabidiol theactivemetaboliteofbenzodiazepines

increases exposure

Moderate Study

cannabidiol theactivemetaboliteofclobazamandclobazamincreasestheexposuretotheactivemetaboliteofcannabidiol

increases exposure

Moderate Study

cannabidiol valproate

increases risk of increasedaltconcentrations

Moderate Study

capecitabine coumarins

increases effects

Moderate Anecdotal

carbamazepine antifungals,azoles

decreases efficacy

Moderate Theoretical

carbamazepine antipsychotics,secondgeneration

decreases exposure

Moderate Study

carbamazepine atorvastatin

decreases exposure

Moderate Study

carbamazepine coumarins

decreases effects

Moderate Study

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1418 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.