Drug Interactions Database
3916 interactions from BNF 85 - Check your medicines
Source:
BNF 85
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
combinedhormonalcontraceptives
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
cyproterone
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
cyproteronewithethinylestradiol
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
desogestrel
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
estradiol
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
etonogestrel
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
hormonereplacementtherapy
decreases effects
Unknown
Anecdotal
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
levonorgestrel
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
norethisterone
decreases efficacy
Unknown
Anecdotal
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
phenobarbital,phenytoin,primidone
sorafenib
decreases exposure
Unknown
Theoretical
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
antiarrhythmics
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
ergotamine
decreases effects
Unknown
Theoretical
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
etoposide
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
ponesimod
decreases exposure
Unknown
Theoretical
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
propafenone
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
canagliflozin
decreases exposure
Unknown
Study
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
procarbazine
increases risk of hypersensitivityreactions
Unknown
Anecdotal
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
rivaroxaban
decreases exposure
Unknown
Study
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
sodiumglucoseco-transporter
decreases exposure
Unknown
Study
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
antipsychotics,secondgeneration
decreases exposure
Unknown
Anecdotal
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
clozapine
decreases exposure
Unknown
Anecdotal
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
dapsone
increases risk of methaemoglobinaemia
Unknown
Theoretical
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
dolutegravir
decreases exposure
Unknown
Study
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
edoxaban
decreases exposure
Unknown
Theoretical
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
fenfluramine
decreases exposure
Unknown
Theoretical
antiepilepticsdecreasetheexposureto
e voriconazoleandvoriconazole
antiepileptics
increases exposure
Unknown
Study
antiepilepticsdecreasetheexposureto
e voriconazoleandvoriconazole
fosphenytoin
increases exposure
Unknown
Study
antiepilepticsdecreasetheexposuretovoriconazole
andvoriconazole
antiepileptics
increases exposure
Unknown
Study
antiepilepticsdecreasetheexposuretovoriconazole
andvoriconazole
phenytoin
increases exposure
Unknown
Study
antiepilepticsslightlydecreasetheexposure
toefavirenzandefavirenz
antiepileptics
decreases exposure
Unknown
Study
antiepilepticsslightlydecreasetheexposure
toefavirenzandefavirenz
carbamazepine
decreases exposure
Unknown
Study
antifungals,azoles
abemaciclib
increases exposure
Unknown
Study
antifungals,azoles
alphablockers
increases exposure
Unknown
Theoretical
antifungals,azoles
alprazolam
increases exposure
Unknown
Study
antifungals,azoles
antihistamines,non-sedating
increases exposure
Unknown
Theoretical
antifungals,azoles
apixaban
increases risk of bleeding
Unknown
Study
antifungals,azoles
avanafil
increases exposure
Unknown
Theoretical
antifungals,azoles
avapritinib
increases exposure
Unknown
Study
antifungals,azoles
axitinib
increases exposure
Unknown
Study
antifungals,azoles
benzodiazepines
increases exposure
Unknown
Study
antifungals,azoles
brigatinib
increases exposure
Unknown
Study
antifungals,azoles
bromocriptine
increases exposure
Unknown
Theoretical
antifungals,azoles
cabazitaxel
increases exposure
Unknown
Theoretical
antifungals,azoles
ceritinib
increases exposure
Unknown
Study
antifungals,azoles
ciclosporin
increases concentration
Unknown
Study
antifungals,azoles
cobimetinib
increases exposure
Unknown
Study
antifungals,azoles
colchicine
increases exposure
Unknown
Study
antifungals,azoles
dabrafenib
increases exposure
Unknown
Study
antifungals,azoles
dapoxetine
increases exposure
Unknown
Theoretical
antifungals,azoles
dasatinib
increases exposure
Unknown
Study
Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.