Drug Interactions Database

6278 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

letermovir sirolimus

increases concentration

Moderate Study

letermovir tezacaftor

increases exposure

Moderate Study

letermovir vardenafil

increases exposure

Moderate Theoretical

letermovir venetoclax

increases exposure

Moderate Study

letermovir warfarin

decreases concentration

Moderate Theoretical

letermovir zopiclone

increases exposure

Moderate Study

livevaccines diroximelfumarate

increases risk of generalisedinfection(possiblylife-threatening)

Moderate Theoretical

lomitapide coumarins

increases exposure

Moderate Study

lomitapide simvastatin

increases exposure

Moderate Study

lomitapide warfarin

increases exposure

Moderate Study

lumacaftor bupropion

decreases exposure

Moderate Theoretical

lumacaftor corticosteroids

decreases exposure

Moderate Theoretical

lumacaftor methylprednisolone

decreases exposure

Moderate Theoretical

lumacaftor rifabutin

decreases exposure

Moderate Theoretical

lumacaftor rifamycins

decreases exposure

Moderate Theoretical

macrolides bictegravir

increases exposure

Moderate Theoretical

mao-binhibitors levodopa

increases effects

Moderate Study

methylphenidate tricyclicantidepressants

increases concentration

Moderate Study

metreleptin insulin

increases risk of hypoglycaemia

Moderate Theoretical

metreleptin sulfonylureas

increases risk of hypoglycaemia

Moderate Theoretical

metronidazole coumarins

increases anticoagulant effect

Moderate Study

metronidazole lithium

increases concentration

Moderate Anecdotal

mexiletine aminophylline

increases exposure

Moderate Theoretical

mexiletine antipsychotics,secondgeneration

increases concentration

Moderate Study

mexiletine antipsychotics,secondgeneration

increases exposure

Moderate Anecdotal

mexiletine clozapine

increases concentration

Moderate Study

mexiletine dopaminereceptoragonists

increases exposure

Moderate Study

mexiletine erlotinib

increases exposure

Moderate Study

mexiletine olanzapine

increases exposure

Moderate Anecdotal

mexiletine pirfenidone

increases exposure

Moderate Study

mexiletine ropinirole

increases exposure

Moderate Study

mexiletine theophylline

increases exposure

Moderate Theoretical

miconazole alfentanil

increases exposure

Moderate Theoretical

miconazole alkylatingagents

increases concentration

Moderate Theoretical

miconazole alprazolam

increases exposure

Moderate Theoretical

miconazole amlodipine

increases exposure

Moderate Theoretical

miconazole antiarrhythmics

increases exposure

Moderate Theoretical

miconazole benzodiazepines

increases exposure

Moderate Theoretical

miconazole buspirone

increases concentration

Moderate Theoretical

miconazole busulfan

increases concentration

Moderate Theoretical

miconazole calciumchannelblockers

increases exposure

Moderate Theoretical

miconazole ciclosporin

increases concentration

Moderate Anecdotal

miconazole cilostazol

increases exposure

Moderate Theoretical

miconazole corticosteroids

increases concentration

Moderate Theoretical

miconazole disopyramide

increases exposure

Moderate Theoretical

miconazole docetaxel

increases concentration

Moderate Theoretical

miconazole felodipine

increases exposure

Moderate Theoretical

miconazole intravenousbenzodiazepines

increases exposure

Moderate Theoretical

miconazole lacidipine

increases exposure

Moderate Theoretical

miconazole lercanidipine

increases exposure

Moderate Theoretical

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6278 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.