Drug Interactions Database

6278 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

clarithromycin simvastatin

increases exposure

Severe Study

clarithromycin sirolimus

increases concentration

Severe Study

clarithromycin temsirolimus

increases concentration

Severe Theoretical

clarithromycin tolterodine

increases exposure

Severe Study

clarithromycin trastuzumabemtansine

increases exposure

Severe Theoretical

clarithromycinvery antiarrhythmics

increases exposure

Severe Study

clarithromycinvery dronedarone

increases exposure

Severe Study

cobicistat acalabrutinib

increases exposure

Severe Study

cobicistat antifungals,azoles

affects exposure

Severe Theoretical

cobicistat antihistamines,non-sedating

increases exposure

Severe Study

cobicistat antipsychotics,secondgeneration

increases exposure

Severe Study

cobicistat benzodiazepines

increases exposure

Severe Study

cobicistat beta

increases exposure

Severe Study

cobicistat cariprazine

increases exposure

Severe Study

cobicistat combinedhormonalcontraceptives

decreases efficacy

Severe Study

cobicistat dabigatran

increases exposure

Severe Study

cobicistat domperidone

increases exposure

Severe Study

cobicistat eletriptan

increases exposure

Severe Study

cobicistat eplerenone

increases exposure

Severe Study

cobicistat finerenone

increases exposure

Severe Study

cobicistat lercanidipine

increases exposure

Severe Study

cobicistat lomitapide

increases exposure

Severe Study

cobicistat lurasidone

increases exposure

Severe Study

cobicistat mineralocorticoidreceptorantagonists

increases exposure

Severe Study

cobicistat mobocertinib

increases exposure

Severe Study

cobicistat naloxegol

increases exposure

Severe Study

cobicistat phosphodiesterasetype-

increases exposure

Severe Study

cobicistat quetiapine

increases exposure

Severe Study

cobicistat simvastatin

increases exposure

Severe Study

cobicistat sirolimus

increases concentration

Severe Study

cobicistat temsirolimus

increases concentration

Severe Theoretical

cobicistat theactivemetaboliteofclopidogrel

decreases concentration

Severe Theoretical

cobicistat thrombininhibitors

increases exposure

Severe Study

cobicistat ticagrelor

increases exposure

Severe Study

cobicistat trastuzumabemtansine

increases exposure

Severe Theoretical

cobicistatvery antiarrhythmics

increases exposure

Severe Study

cobicistatvery dronedarone

increases exposure

Severe Study

combinedhormonalcontraceptives lenalidomide

increases risk of venousthromboembolism

Severe Theoretical

combinedhormonalcontraceptives pomalidomide

increases risk of venousthromboembolism

Severe Theoretical

combinedhormonalcontraceptives thalidomide

increases risk of venousthromboembolism

Severe Study

combinedhormonalcontraceptives tizanidine

increases exposure

Severe Study

combinedhormonalcontraceptives(containing ethinylestradiol voxilaprevirwithsofosbuvirandvelpatasvir

increases risk of increasedaltconcentrations

Severe Study

corticosteroids mifamurtide

decreases efficacy

Severe Theoretical

crizotinib antipsychotics,secondgeneration

increases exposure

Severe Study

crizotinib domperidone

increases exposure

Severe Study

cyclophosphamide pentostatin

increases risk of toxicity

Severe Anecdotal

cyproheptadine metyrapone

decreases effects

Severe Study

cytarabine flucytosine

decreases concentration

Severe Study

dabrafenib anti-androgens

decreases exposure

Severe Theoretical

dabrafenib antifungals,azoles

decreases exposure

Severe Theoretical

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6278 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.