Drug Interactions Database

6278 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

stjohn’swort carbamazepine

decreases concentration

Moderate Theoretical

stjohn’swort dronabinol

decreases exposure

Moderate Study

stjohn’swort everolimus

decreases concentration

Moderate Study

stjohn’swort felodipine

decreases exposure

Moderate Theoretical

stjohn’swort guanfacine

decreases concentration

Moderate Theoretical

stjohn’swort lacidipine

decreases exposure

Moderate Theoretical

stjohn’swort lercanidipine

decreases exposure

Moderate Theoretical

stjohn’swort lurasidone

decreases exposure

Moderate Theoretical

stjohn’swort methadone

decreases exposure

Moderate Study

stjohn’swort midazolam

decreases exposure

Moderate Study

stjohn’swort nicardipine

decreases exposure

Moderate Theoretical

stjohn’swort nifedipine

decreases exposure

Moderate Theoretical

stjohn’swort nimodipine

decreases exposure

Moderate Theoretical

stjohn’swort opioids

decreases exposure

Moderate Study

stjohn’swort oxycodone

decreases exposure

Moderate Study

stjohn’swort perampanel

decreases exposure

Moderate Theoretical

stjohn’swort pitolisant

decreases exposure

Moderate Theoretical

stjohn’swort pralsetinib

decreases exposure

Moderate Study

stjohn’swort ripretinib

decreases exposure

Moderate Theoretical

stjohn’swort ruxolitinib

decreases exposure

Moderate Study

stjohn’swort sirolimus

decreases concentration

Moderate Theoretical

stjohn’swort treprostinil

decreases exposure

Moderate Theoretical

sulfadiazine antiepileptics

increases concentration

Moderate Study

sulfadiazine fosphenytoin

increases concentration

Moderate Study

sulfadiazine phenytoin

increases concentration

Moderate Study

sulfonamides methotrexate

increases exposure

Moderate Theoretical

sulindac cladribine

increases exposure

Moderate Theoretical

tegafur antiepileptics

increases concentration

Moderate Anecdotal

tegafur fosphenytoin

increases concentration

Moderate Anecdotal

tegafur phenytoin

increases concentration

Moderate Anecdotal

terbinafine anticholinesterases,centrallyacting

increases exposure

Moderate Study

terbinafine antipsychotics,secondgeneration

increases exposure

Moderate Study

terbinafine atomoxetine

increases exposure

Moderate Study

terbinafine eliglustat

increases exposure

Moderate Study

terbinafine fesoterodine

increases exposure

Moderate Theoretical

terbinafine fluoxetine

increases exposure

Moderate Theoretical

terbinafine galantamine

increases exposure

Moderate Study

terbinafine risperidone

increases exposure

Moderate Study

terbinafine tricyclicantidepressants

increases exposure

Moderate Study

terbinafine vortioxetine

increases exposure

Moderate Study

teriflunomide cladribine

increases exposure

Moderate Theoretical

teriflunomide olanzapine

decreases exposure

Moderate Study

teriflunomide theophylline

decreases exposure

Moderate Study

tetrabenazine levodopa

decreases effects

Moderate Theoretical

tetracyclines lithium

increases risk of lithiumtoxicity

Moderate Anecdotal

theophylline lithium

decreases concentration

Moderate Anecdotal

thyroidhormones digoxin

affects concentration

Moderate Theoretical

ticagrelor dabigatran

increases exposure

Moderate Study

ticagrelor thrombininhibitors

increases exposure

Moderate Study

tocilizumab alprazolam

decreases exposure

Moderate Theoretical

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6278 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.