Drug Interactions Database
6278 interactions from BNF 85 - Check your medicines
Source:
BNF 85
antiarrhythmics
vincaalkaloids
increases exposure
Unknown
Theoretical
antiarrhythmics(amiodarone,disopyramide,dronedarone,
flecainide,lidocaine
betablockers
increases risk of cardiovascularadverseeffects
Unknown
antiarrhythmicsgivenwithapotentcyp2c19
inhibitor
tofacitinib
increases exposure
Unknown
Study
anticholinesterases,centrallyacting
neuromuscularblockingdrugs,non-depolarising
decreases effects
Unknown
Theoretical
antiepileptics
desmopressin
increases risk of hyponatraemia
Unknown
Theoretical
antiepileptics
empagliflozin
decreases exposure
Unknown
Theoretical
antiepileptics
etonogestrel
decreases effects
Unknown
Theoretical
antiepileptics
levonorgestrel
decreases effects
Unknown
Theoretical
antiepileptics
norethisterone
decreases effects
Unknown
Theoretical
antiepileptics
tigecycline
decreases exposure
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
anti-androgens
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
co-cyprindiol
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
combinedhormonalcontraceptives
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
cyproterone
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
cyproteronewithethinylestradiol
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
desogestrel
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
estradiol
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
etonogestrel
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
hormonereplacementtherapy
decreases effects
Unknown
Anecdotal
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
levonorgestrel
decreases efficacy
Unknown
Theoretical
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
oxcarbazepine,perampanel,phenobarbital,phenytoin,
primidone,rufinamide,topiramate
norethisterone
decreases efficacy
Unknown
Anecdotal
antiepileptics(carbamazepine,eslicarbazepine,fosphenytoin,
phenobarbital,phenytoin,primidone
sorafenib
decreases exposure
Unknown
Theoretical
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
antiarrhythmics
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
ergotamine
decreases effects
Unknown
Theoretical
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
etoposide
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
ponesimod
decreases exposure
Unknown
Theoretical
antiepileptics(carbamazepine,fosphenytoin,phenobarbital,
phenytoin,primidone
propafenone
decreases efficacy
Unknown
Study
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
canagliflozin
decreases exposure
Unknown
Study
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
procarbazine
increases risk of hypersensitivityreactions
Unknown
Anecdotal
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
rivaroxaban
decreases exposure
Unknown
Study
antiepileptics(carbamazepine,phenobarbital,phenytoin,
primidone
sodiumglucoseco-transporter
decreases exposure
Unknown
Study
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
antipsychotics,secondgeneration
decreases exposure
Unknown
Anecdotal
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
clozapine
decreases exposure
Unknown
Anecdotal
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
dapsone
increases risk of methaemoglobinaemia
Unknown
Theoretical
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
dolutegravir
decreases exposure
Unknown
Study
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
edoxaban
decreases exposure
Unknown
Theoretical
antiepileptics(fosphenytoin,phenobarbital,phenytoin,
primidone
fenfluramine
decreases exposure
Unknown
Theoretical
antiepilepticsdecreasetheexposureto
e voriconazoleandvoriconazole
antiepileptics
increases exposure
Unknown
Study
antiepilepticsdecreasetheexposureto
e voriconazoleandvoriconazole
fosphenytoin
increases exposure
Unknown
Study
antiepilepticsdecreasetheexposuretovoriconazole
andvoriconazole
antiepileptics
increases exposure
Unknown
Study
antiepilepticsdecreasetheexposuretovoriconazole
andvoriconazole
phenytoin
increases exposure
Unknown
Study
antiepilepticsslightlydecreasetheexposure
toefavirenzandefavirenz
antiepileptics
decreases exposure
Unknown
Study
antiepilepticsslightlydecreasetheexposure
toefavirenzandefavirenz
carbamazepine
decreases exposure
Unknown
Study
antifungals,azoles
abemaciclib
increases exposure
Unknown
Study
antifungals,azoles
alphablockers
increases exposure
Unknown
Theoretical
antifungals,azoles
alprazolam
increases exposure
Unknown
Study
antifungals,azoles
antihistamines,non-sedating
increases exposure
Unknown
Theoretical
antifungals,azoles
apixaban
increases risk of bleeding
Unknown
Study
antifungals,azoles
avanafil
increases exposure
Unknown
Theoretical
antifungals,azoles
avapritinib
increases exposure
Unknown
Study
Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.