Drug Interactions Database

1418 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

crizotinib tezacaftor

increases exposure

Moderate Study

crizotinib vardenafil

increases exposure

Moderate Theoretical

crizotinib venetoclax

increases exposure

Moderate Study

crizotinib zopiclone

increases exposure

Moderate Study

cycloserine isoniazid

increases risk of cnstoxicity

Moderate Study

dabrafenib amlodipine

decreases exposure

Moderate Theoretical

dabrafenib benzodiazepines

decreases exposure

Moderate Study

dabrafenib calciumchannelblockers

decreases exposure

Moderate Theoretical

dabrafenib everolimus

decreases concentration

Moderate Study

dabrafenib felodipine

decreases exposure

Moderate Theoretical

dabrafenib guanfacine

decreases concentration

Moderate Theoretical

dabrafenib lacidipine

decreases exposure

Moderate Theoretical

dabrafenib lercanidipine

decreases exposure

Moderate Theoretical

dabrafenib lurasidone

decreases exposure

Moderate Theoretical

dabrafenib methadone

decreases exposure

Moderate Study

dabrafenib midazolam

decreases exposure

Moderate Study

dabrafenib nicardipine

decreases exposure

Moderate Theoretical

dabrafenib nifedipine

decreases exposure

Moderate Theoretical

dabrafenib nimodipine

decreases exposure

Moderate Theoretical

dabrafenib opioids

decreases exposure

Moderate Study

dabrafenib osimertinib

decreases exposure

Moderate Study

dabrafenib ripretinib

decreases exposure

Moderate Theoretical

dabrafenib ruxolitinib

decreases exposure

Moderate Study

dacomitinib atomoxetine

increases exposure

Moderate Study

dacomitinib eliglustat

increases exposure

Moderate Study

dapsone prilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical

dapsone topicalanaesthetics,local

increases risk of methaemoglobinaemia

Moderate Theoretical

dapsone topicalprilocaine

increases risk of methaemoglobinaemia

Moderate Theoretical

deferasirox treprostinil

increases exposure

Moderate Theoretical

diazepampotentially antiepileptics

affects concentration

Moderate Study

diazepampotentially fosphenytoin

affects concentration

Moderate Study

diazepampotentially phenytoin

affects concentration

Moderate Study

diazoxide antiepileptics

decreases concentration

Moderate Anecdotal

diazoxide fosphenytoin

decreases concentration

Moderate Anecdotal

diazoxide phenytoin

decreases concentration

Moderate Anecdotal

diltiazem antiepileptics

increases concentration

Moderate Anecdotal

diltiazem atorvastatin

increases exposure

Moderate Study

diltiazem carbamazepine

increases concentration

Moderate Anecdotal

diltiazem fostamatinib

increases exposure

Moderate Theoretical

diltiazem statins

increases exposure

Moderate Study

dipyridamole adenosine

increases exposure

Moderate Study

dipyridamole antiarrhythmics

increases exposure

Moderate Study

disulfiram antiepileptics

increases concentration

Moderate Study

disulfiram coumarins

increases anticoagulant effect

Moderate Study

disulfiram fosphenytoin

increases concentration

Moderate Study

disulfiram phenytoin

increases concentration

Moderate Study

dolutegravir dopaminereceptoragonists

increases exposure

Moderate Study

dolutegravir metformin

increases exposure

Moderate Study

dolutegravir pramipexole

increases exposure

Moderate Study

doravirine sirolimus

decreases exposure

Moderate Theoretical

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1418 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.