Drug Interactions Database

944 interactions from BNF 85 - Check your medicines

Source: BNF 85

Severity: All 6278 Severe 944 Moderate 1418 Unknown 3916

abatacept golimumab

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

abatacept monoclonalantibodies

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

aceinhibitors icatibantandicatibantispredictedtodecreasetheefficacyof

decreases efficacy

Severe Theoretical

acetazolamide methenamine

decreases efficacy

Severe Theoretical

acitretin methotrexate

increases concentration

Severe Anecdotal

alemtuzumab fingolimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

alemtuzumab ozanimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

alemtuzumab siponimod

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

aluminiumhydroxide deferasirox

decreases exposure

Severe Theoretical

amfetamines apraclonidine

decreases effects

Severe Theoretical

amfetamines moclobemide

increases risk of ahypertensivecrisis

Severe Theoretical

aminoglycosides agalsidasealfa

decreases effects

Severe Theoretical

aminoglycosides agalsidasebeta

decreases effects

Severe Theoretical

aminophylline phosphodiesterasetype-

increases exposure

Severe Theoretical

aminophylline roflumilast

increases exposure

Severe Theoretical

amiodarone agalsidasealfa

decreases effects

Severe Theoretical

amiodarone agalsidasebeta

decreases effects

Severe Theoretical

amiodarone calciumchannelblockers

increases risk of cardiodepression

Severe Theoretical

amiodarone diltiazem

increases risk of cardiodepression

Severe Theoretical

amiodarone thyroidhormones

increases risk of thyroiddysfunction

Severe Study

amiodarone verapamil

increases risk of cardiodepression

Severe Theoretical

amitriptyline metyrapone

decreases effects

Severe Theoretical

anakinra etanercept

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

anakinra golimumab

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

anakinra monoclonalantibodies

increases risk of generalisedinfection(possiblylife-threatening)

Severe Theoretical

anthracyclines monoclonalantibodies

increases risk of cardiotoxicity

Severe Theoretical

anthracyclines trastuzumab

increases risk of cardiotoxicity

Severe Theoretical

anthracyclines trastuzumabemtansine

increases risk of cardiotoxicity

Severe Theoretical

antiepileptics(carbamazepine,fosphenytoin,oxcarbazepine, phenobarbital,phenytoin,primidone imatinib

decreases exposure

Severe Study

antiepileptics(carbamazepine,fosphenytoin,oxcarbazepine, phenobarbital,phenytoin,primidone tenofoviralafenamide

decreases exposure

Severe Theoretical

antiepileptics(carbamazepine,fosphenytoin,phenobarbital, phenytoin,primidone elexacaftor

decreases exposure

Severe Theoretical

antiepileptics(carbamazepine,fosphenytoin,phenobarbital, phenytoin,primidone remdesivir

decreases exposure

Severe Theoretical

antiepileptics(carbamazepine,fosphenytoin,phenobarbital, phenytoin,primidone tepotinib

decreases exposure

Severe Theoretical

antiepileptics(fosphenytoin,phenobarbital,phenytoin, primidone metyrapone

decreases effects

Severe Study

antifungals,azoles acalabrutinib

increases exposure

Severe Study

antifungals,azoles antipsychotics,secondgeneration

increases exposure

Severe Study

antifungals,azoles bedaquiline

increases exposure

Severe Theoretical

antifungals,azoles cariprazine

increases exposure

Severe Study

antifungals,azoles entrectinib

increases exposure

Severe Theoretical

antifungals,azoles lomitapide

increases exposure

Severe Theoretical

antifungals,azoles mobocertinib

increases exposure

Severe Study

antifungals,azoles neratinib

increases exposure

Severe Study

antifungals,azoles olaparib

increases exposure

Severe Theoretical

antifungals,azoles pimozide

increases exposure

Severe Theoretical

antifungals,azoles quetiapine

increases exposure

Severe Study

antifungals,azoles rimegepant

increases exposure

Severe Study

antifungals,azoles tepotinib

increases exposure

Severe Theoretical

antifungals,azoles zanubrutinib

increases exposure

Severe Theoretical

antifungals,azoles(itraconazole,ketoconazole,posaconazole, r voriconazole crizotinib

increases exposure

Severe Study

antifungals,azoles(itraconazole,ketoconazole,posaconazole, voriconazole crizotinib

increases exposure

Severe Study

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944 interactions

Important: This database uses data from the British National Formulary (BNF 85). It is for informational purposes only and is not a substitute for professional medical advice.