What it does
Ascorbic acid, commonly known as vitamin C, is important for overall health and supports the immune system.
Commonly used for: boosting the immune system, preventing or treating vitamin C deficiency, supporting skin health
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:41 · updated 2026-09-29 04:33:05
About ascorbic
Ascorbic acid, commonly known as vitamin C, is important for overall health and supports the immune system.
What it treats
- boosting the immune system
- preventing or treating vitamin C deficiency
- supporting skin health
How it works
Vitamin C helps the body form collagen and absorb iron, and it also acts as an antioxidant to protect cells from damage.
Who it's for
It is suitable for most people, especially those who may not get enough vitamin C from their diet.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About ihs
Ihs is a medication used to treat certain health conditions.
How it works
Ihs works by affecting specific processes in the body to help manage symptoms or treat a condition.
Who it's for
Ihs is prescribed for patients with specific medical conditions as determined by a healthcare provider.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: ascorbic
Ascorbic acid, commonly known as vitamin C, is a water-soluble vitamin essential for various physiological functions in the human body. It acts as a powerful antioxidant, helping to protect cells from oxidative stress and contributing to the maintenance of healthy skin, blood vessels, bones, and cartilage. Additionally, ascorbic acid plays a critical role in the synthesis of collagen, neurotransmitters, and certain hormones. It is commonly found in fruits and vegetables, and supplementation is often used to prevent or treat vitamin C deficiency, such as scurvy.
Indications
- Vitamin C deficiency
- Scurvy
- As an adjunct in the treatment of iron deficiency anemia
- Support for immune function
- Antioxidant therapy
Dosage
Adults: Refer to the BNF for specific
Mechanism of action
Ascorbic acid functions primarily as a reducing agent, donating electrons to various biochemical reactions. It is involved in the hydroxylation of proline and lysine residues in collagen synthesis, which is essential for maintaining connective tissue integrity. As an antioxidant, it also helps to regenerate other antioxidants, such as vitamin E, thereby protecting cells from oxidative damage. Furthermore, it enhances the absorption of non-heme iron from the gastrointestinal tract, promoting better iron utilization in the body.
Pharmacodynamics
Ascorbic acid is crucial for metabolic processes, including the synthesis of collagen and certain neurotransmitters. Its antioxidant properties help mitigate oxidative stress, which can lead to cellular damage and various diseases. The vitamin's role in iron absorption is particularly significant in preventing iron-deficiency anemia. The therapeutic effects of ascorbic acid are dose-dependent, with higher doses often resulting in more pronounced antioxidant effects.
Pharmacokinetics
Ascorbic acid is readily absorbed in the small intestine, with peak plasma concentrations occurring within 2 to 4 hours after oral administration. The bioavailability of ascorbic acid decreases at higher doses due to saturation of the transport mechanisms. It is distributed throughout bodily fluids and tissues, with highest concentrations found in the adrenal glands, pituitary gland, and leukocytes. The elimination half-life varies, typically ranging from 8 to 40 days, depending on the dose and the individual's renal function. Ascorbic acid is excreted primarily through the kidneys, with renal clearance being influenced by plasma concentration and renal health.
Interactions
- ascorbic acid + iron chelators: Unknown (increases risk of cardiovascular adverse effects)
- ascorbic acid + deferiprone: Unknown (increases risk of cardiovascular adverse effects)
- ascorbic acid + desferrioxamine: Unknown (increases risk of cardiovascular adverse effects)
Pregnancy
Ascorbic acid is generally considered safe during pregnancy but should be used with caution and only when necessary.
Breast-feeding
Ascorbic acid is excreted in breast milk and is generally considered safe during breastfeeding.
Storage
Store at room temperature, away from light and moisture.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
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