What it does
Calamine is a topical skin treatment commonly used to soothe and relieve irritation and itching.
Commonly used for: itchy skin, sunburn, insect bites, chickenpox …
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 20:40:20 · updated 2026-07-26 11:30:53
About this medicine
Calamine is a topical skin treatment commonly used to soothe and relieve irritation and itching.
What it treats
- itchy skin
- sunburn
- insect bites
- chickenpox
- eczema
How it works
Calamine works by cooling the skin and providing a protective barrier to reduce irritation.
Who it's for
Calamine is suitable for adults and children who need relief from mild skin irritations.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: calamine
BNF-referencedCalamine is a topical medication primarily used for its soothing properties in the treatment of minor skin irritations, including insect bites, sunburn, and rashes. It typically contains a mixture of zinc oxide and ferric oxide, which contribute to its protective and anti-itching effects.
Indications
- Mild skin irritations
- Insect bites
- Sunburn
- Rashes
- Prickly heat
Dosage
Children: Refer to the BNF for Children for appropriate dosing guidelines based on age and condition.
Adults: Apply to the affected area as needed, usually 2 to 4 times daily.
Mechanism of action
Calamine exerts its effects mainly through the astringent properties of zinc oxide and the soothing effects of ferric oxide. It helps to dry out oozing and weeping skin, while also providing a cooling sensation to alleviate discomfort.
Pharmacodynamics
The pharmacodynamics of calamine involve its ability to act as a protective barrier on the skin, reducing irritation and discomfort associated with various skin conditions. The astringent properties help to reduce moisture and inflammation, making it effective for soothing skin irritations.
Pharmacokinetics
Calamine is applied topically and is not significantly absorbed into systemic circulation, which minimizes systemic side effects. Its local effects are immediate upon application, providing rapid relief from symptoms like itching and inflammation.
Pregnancy
Calamine is generally considered safe for use during pregnancy, as it is a topical agent with limited systemic absorption.
Breast-feeding
Calamine is also considered safe for use during breastfeeding, as it is unlikely to pose a risk to the nursing infant.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Formulations
- Calamine lotion
- Calamine cream
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Molecular reference: calamine
PubChem CID 23083748Molecular formula: Fe2O4Zn
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.
- CALAMINE 15%W/V LOTION
- CALAMINE 150MG LOTION
- CALAMINE COMBINATION PRODUCT LOTION
- CALAMINE COMBINATION PRODUCT LOTION
- CALAMINE COMBINATION PRODUCT LOTION
- CALAMINE&SULPHUR 2% LOTION