What it does
Feropenum is a medication used to treat iron deficiency anemia, a condition where the body lacks enough iron to produce healthy red blood cells.
Commonly used for: iron deficiency anemia
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 21:29:55 · updated 2026-07-20 11:04:03
About this medicine
Feropenum is a medication used to treat iron deficiency anemia, a condition where the body lacks enough iron to produce healthy red blood cells.
What it treats
- iron deficiency anemia
How it works
Feropenum helps to increase the level of iron in the body, which is essential for making red blood cells.
Who it's for
It is typically prescribed for individuals who have low iron levels, especially those with anemia.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: feropenum
Feropenum is a parenteral iron preparation used for the treatment and prevention of iron deficiency anemia. It is particularly useful for patients who cannot tolerate oral iron formulations or have conditions that require rapid replenishment of iron stores. It is administered via injection, allowing for direct delivery into the bloodstream, which can be beneficial in acute situations.
Indications
- Iron deficiency anemia
- Post-surgical anemia
- Anemia due to chronic disease
- Anemia in pregnant women
- Anemia related to gastrointestinal disorders
Dosage
Children: Refer to the BNF for Children for appropriate dosing guidelines based on the child's age, weight, and clinical condition.
Adults: Refer to specific guidelines and consult the BNF for recommended dosing based on individual patient needs and clinical scenarios.
Mechanism of action
Feropenum works primarily by providing elemental iron, which is essential for hemoglobin synthesis and the production of red blood cells. Once administered, it is dissociated in the body to release iron, which then gets incorporated into hemoglobin and myoglobin, facilitating oxygen transport and storage in tissues.
Pharmacodynamics
The pharmacodynamic effects of feropenum include the replenishment of iron stores in the body, leading to increased hemoglobin levels and improvement in the symptoms associated with iron deficiency anemia, such as fatigue and weakness. The effectiveness can be observed within a few days of administration, although full repletion of iron stores may take several weeks.
Pharmacokinetics
After administration, feropenum is rapidly absorbed and distributed in the body’s compartments. It binds to transferrin, a plasma protein that transports iron, and is delivered to various tissues, notably the bone marrow where erythropoiesis occurs. The half-life of iron in the body can vary depending on the individual's iron status and the presence of any underlying conditions affecting iron metabolism. Excretion primarily occurs through the gastrointestinal tract, and any excess iron is stored in the liver, spleen, and bone marrow.
Contra-indications
- Hypersensitivity to feropenum or any of its excipients
- History of iron overload disorders such as hemochromatosis or hemosiderosis
Adverse effects
- Gastrointestinal disturbances
- Nausea
- Vomiting
- Constipation
- Diarrhea
- Stomach cramps
- Dark stools
- Allergic reactions
Interactions
- Antacids may reduce the absorption of feropenum
- Tetracycline antibiotics may interact and decrease effectiveness
- Calcium supplements may interfere with iron absorption
Precautions
- Use with caution in patients with gastrointestinal disorders
- Monitor hemoglobin levels in patients with severe anemia
- Consider alternative therapies in patients with a history of peptic ulcer disease
Pregnancy
Feropenum is generally considered safe for use during pregnancy to treat iron deficiency anemia, but should be used under medical supervision.
Breast-feeding
Feropenum is excreted in breast milk; however, it is unlikely to affect a nursing infant when used at recommended doses.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Formulations
- Oral tablets
- Oral solution
- Intravenous formulation
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.