What it does
Chitosan is a natural substance derived from shellfish that is often used as a dietary supplement.
Commonly used for: weight loss, cholesterol management, digestive health
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Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:42 · updated 2026-09-29 04:33:05
About this medicine
Chitosan is a natural substance derived from shellfish that is often used as a dietary supplement.
What it treats
- weight loss
- cholesterol management
- digestive health
How it works
Chitosan works by binding to fats in the digestive system, which may help reduce fat absorption and support weight loss.
Who it's for
Chitosan is suitable for adults looking to manage their weight or improve their cholesterol levels.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: chitosan
Chitosan is a biopolymer derived from chitin, which is found in the exoskeletons of crustaceans. It is known for its ability to bind fats and cholesterol, which may aid in weight management and cholesterol reduction. Chitosan is often marketed as a dietary supplement for weight loss and is used in various formulations due to its potential health benefits.
Indications
- Weight management
- Reduction of cholesterol levels
- Support in dietary fat absorption
Dosage
Children: Refer to specific product guidelines as pediatric dosages are not well established.
Adults: Refer to specific product guidelines as dosages may vary widely based on formulation and concentration.
Mechanism of action
Chitosan acts primarily through its ability to bind dietary fats and cholesterol in the gastrointestinal tract, forming a complex that is not absorbed by the body. This mechanism reduces the absorption of fats and can lead to decreased calorie intake. Additionally, it may influence lipid metabolism and promote fat excretion.
Pharmacodynamics
Chitosan exhibits a high degree of biocompatibility and is non-toxic, which allows it to be safely ingested. Its lipid-binding properties contribute to a reduction in serum cholesterol levels and may help in weight management. The effects on lipid profiles are attributed to its ability to inhibit the absorption of dietary lipids and cholesterol.
Pharmacokinetics
Chitosan is not absorbed through the gastrointestinal tract due to its high molecular weight and polymeric structure. It passes through the digestive system largely unchanged. The effects of chitosan are primarily localized to the gut, where it interacts with dietary fats and cholesterol. Its elimination is through fecal excretion.
Adverse effects
- Gastrointestinal discomfort
- Nausea
- Constipation
- Diarrhea
- Flatulence
Precautions
- Use with caution in individuals with shellfish allergies, as chitosan is derived from chitin found in shellfish.
- Monitor for gastrointestinal side effects, particularly in patients with pre-existing digestive disorders.
Pregnancy
Chitosan is generally considered safe in pregnancy, but its effects have not been extensively studied. Consultation with a healthcare provider is recommended.
Breast-feeding
Chitosan is likely safe during breastfeeding, but limited data are available. Consultation with a healthcare provider is recommended.
Storage
Store in a cool, dry place, away from direct sunlight and moisture.
Formulations
- Capsules
- Tablets
- Powder
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.