Registered Malawi · PMRA

CORASIL COMBINATION PRODUCT TABLET

MAGNESIUM TRILICATE

PMPB/PL252/2 TABLET

What it does

Trilicate is a medication that may be used for various health conditions.

Commonly used for: treating certain types of pain, managing inflammation

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Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.

Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.

Sourcing - Kenya only

Registration & product details

Registration no.
PMPB/PL252/2
Registration date
12/09/2002
Expiry date
30/06/2007
Status
Registered
Active ingredient
MAGNESIUM TRILICATE
Dosage form
TABLET
Strength
-
Pack size
-
Therapeutic class
-
Manufacturer / MAH
-
Applicant / LTR
-
Country of origin
-

Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:39 · updated 2026-09-29 04:33:04

Disclaimer: This information is sourced from Pharmacy and Medicines Regulatory Authority (Malawi). Always consult a qualified healthcare professional before using any medication.

About this medicine

Trilicate is a medication that may be used for various health conditions.

What it treats

  • treating certain types of pain
  • managing inflammation

How it works

Trilicate works by reducing pain and swelling in the body.

Who it's for

This medication is generally suitable for adults and may be prescribed for specific health issues.

Cautions

  • • Consult your doctor before using if you have any allergies.
  • • Inform your doctor about any other medications you are taking.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: trilicate

Trilicate, also known as a combination of various active ingredients, is primarily used for the treatment of specific gastrointestinal disorders. It often includes antispasmodic and antisecretory components that help alleviate symptoms associated with conditions such as irritable bowel syndrome and other functional gastrointestinal disorders.

Indications

  • Irritable bowel syndrome
  • Functional gastrointestinal disorders
  • Abdominal pain
  • Gastrointestinal spasms

Dosage

Children: Refer to the BNF for Children for appropriate pediatric dosing information.

Adults: Refer to the appropriate prescribing guidelines as specific dosing can vary based on the formulation and patient condition.

Mechanism of action

Trilicate works by inhibiting the action of acetylcholine on muscarinic receptors in the smooth muscle of the gastrointestinal tract, leading to muscle relaxation and reduced motility. Additionally, it may reduce gastric acid secretion and promote gastrointestinal comfort through its antisecretory effects.

Pharmacodynamics

The pharmacodynamic profile of trilicate includes its ability to relieve smooth muscle spasms in the gut, which is beneficial in reducing abdominal pain and discomfort. The drug may also influence the secretion of gastric juices, thereby aiding in the management of hypersecretion-related conditions. The onset of action can vary depending on the specific formulation and route of administration.

Pharmacokinetics

Trilicate is typically well-absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within a few hours after administration. It undergoes hepatic metabolism, where it is conjugated and eliminated via the kidneys. The half-life can vary based on the specific active constituents of the formulation. Patients with hepatic or renal impairment may require dose adjustments.

Pregnancy

Trilicate has not been studied extensively in pregnant women. Use only if the potential benefit justifies the potential risk to the fetus.

Breast-feeding

It is not known whether trilicate is excreted in human milk. Caution is advised when administering to nursing mothers.

Storage

Store at room temperature, away from moisture and heat. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.