CRESOL SAPONATED (LYSOL)
Cresol 50 % w/v
What it does
Cresol is a chemical compound often used as a disinfectant and antiseptic.
Commonly used for: skin infections, wound cleaning, disinfection
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Tanzania Medicines and Medical Devices Authority · fetched 2026-03-11 23:39:34 · updated 2026-10-01 03:00:45
About this medicine
Cresol is a chemical compound often used as a disinfectant and antiseptic.
What it treats
- skin infections
- wound cleaning
- disinfection
How it works
Cresol works by killing bacteria and other harmful germs, helping to prevent infections.
Who it's for
Cresol is typically used by people needing to clean wounds or disinfect areas to prevent infection.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: cresol
Cresol, also known as methylphenol, is a colorless to light yellow aromatic compound with a strong odor. It exists in three isomeric forms: ortho-cresol, meta-cresol, and para-cresol, which differ in the position of the hydroxyl group on the benzene ring. Cresol is primarily used as an antiseptic and disinfectant in various industrial and medicinal applications.
Indications
- Antiseptic
- Disinfectant
- Topical analgesic
- Preservative
- Industrial solvent
Dosage
Children: Refer to specific product guidelines for paediatric dosing, as it varies based on formulation and intended use.
Adults: Refer to specific product guidelines for adult dosing, as it varies based on formulation and intended use.
Mechanism of action
Cresol acts by denaturing proteins and disrupting cellular membranes, which leads to the death of microorganisms. It exhibits broad-spectrum antimicrobial activity against bacteria, fungi, and some viruses. The phenolic structure of cresol contributes to its ability to penetrate lipid membranes, enhancing its efficacy as a disinfectant.
Pharmacodynamics
Cresol demonstrates its antimicrobial effects through cytotoxicity, leading to cell lysis and death. It also has local anesthetic properties, which can provide temporary relief from pain when used in topical formulations. Its antiseptic properties make it effective in reducing microbial load in contaminated wounds or surgical sites.
Pharmacokinetics
Cresol is absorbed through the skin and mucous membranes, and it can be metabolized in the liver to various conjugates. The elimination half-life can vary, but it is generally excreted in urine as glucuronides or sulfates. Due to its lipophilic nature, cresol can accumulate in fatty tissues, which may prolong its effects.
Adverse effects
- Skin irritation
- Respiratory distress
- Gastrointestinal irritation
- CNS depression
- Nausea
- Vomiting
- Headache
- Dizziness
Precautions
- Use with caution in patients with pre-existing respiratory conditions
- Avoid contact with skin and mucous membranes
- Ensure adequate ventilation during use
- Use protective equipment when handling
Pregnancy
Cresol is classified as a category C drug. Its safety in pregnancy has not been established, and it should be used only if the potential benefit justifies the risk to the fetus.
Breast-feeding
It is not known whether cresol is excreted in human milk. Caution should be exercised when it is administered to a nursing woman.
Storage
Store in a cool, dry place away from heat and direct sunlight. Keep container tightly closed and out of reach of children.
Formulations
- Liquid solution
- Topical ointment
- Disinfectant formulations
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.