DAFLON
Esperidin (90 % Diosmin 10 % Of Flavonoids)
What it does
Esperidin is a natural substance often used to support blood vessel health.
Commonly used for: varicose veins, chronic venous insufficiency, hemorrhoids, swelling (edema)
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Rwanda Food and Drugs Authority · fetched 2026-03-11 22:07:39 · updated 2026-09-17 02:30:44
About this medicine
Esperidin is a natural substance often used to support blood vessel health.
What it treats
- varicose veins
- chronic venous insufficiency
- hemorrhoids
- swelling (edema)
How it works
Esperidin helps strengthen blood vessels and improve circulation, which can reduce swelling and discomfort.
Who it's for
It is suitable for adults who have circulation problems or conditions related to blood vessels.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: esperidin
Esperidin is a flavonoid glycoside primarily found in citrus fruits. It is known for its antioxidant properties and is often used to improve vascular health. Esperidin is believed to enhance microcirculation and reduce inflammation, making it beneficial in conditions related to poor venous circulation and capillary fragility.
Indications
- Chronic venous insufficiency
- Hemorrhoids
- Varicose veins
- Leg edema
- Capillary fragility
Dosage
Children: Dosing for pediatric patients should be determined by a healthcare professional, and guidelines should be followed as per clinical recommendations.
Adults: For adults, the typical dosage ranges from 500 mg to 1000 mg per day, depending on the specific condition and formulation. Refer to official guidelines for specific dosing recommendations.
Mechanism of action
Esperidin exerts its effects through various mechanisms, including the modulation of vascular permeability, enhancement of endothelial function, and inhibition of inflammatory mediators. It is known to strengthen blood vessels and promote venous tone, thereby improving blood flow and reducing edema.
Pharmacodynamics
Esperidin has been shown to possess anti-inflammatory, antioxidant, and venotonic properties. It reduces capillary permeability and stabilizes collagen, which helps in protecting blood vessels from damage. Additionally, esperidin may enhance the effects of other flavonoids and improve the overall vascular health.
Pharmacokinetics
After oral administration, esperidin is absorbed in the gastrointestinal tract and undergoes extensive metabolism in the liver. It is primarily excreted as metabolites in urine. The bioavailability of esperidin can be influenced by food intake and the presence of other substances.
Adverse effects
- Gastrointestinal disturbances
- Headache
- Allergic reactions
Precautions
- Use with caution in patients with liver impairment
- Consider potential interactions with other medications
Pregnancy
Safety during pregnancy has not been established. Use only if clearly needed and potential benefits justify the risks.
Breast-feeding
Limited information available. Use with caution and only if benefits outweigh risks.
Storage
Store in a cool, dry place, away from direct sunlight.
Formulations
- Tablets
- Capsules
- Oral solutions
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.