International reference: 2 US FDA recalls for this ingredient
Failed Stability Specifications: Product exceeds compendia and firm's specifications for iron content. (monobasic)
Penicillin Cross Contamination: All lots of all products repackaged and distributed between 01/05/12 and 02/12/15 are being recalled because they were repackaged in a facility with penicillin products without adequate separation which could introduce the potential for cross contamination with penici (monobasic)
US-market enforcement records (OpenFDA), shown for reference - not specific to this product in Botswana.
DERISE 40
Sodium Phosphate Monobasic Monohydrate 0.85 mg
What it does
Monobasic is a compound used in various medical applications.
Commonly used for: pH adjustment in medical solutions, buffering agent in pharmaceutical preparations
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Botswana Medicines Regulatory Authority · fetched 2026-04-15 20:43:07 · updated 2026-10-20 04:32:24
About this medicine
Monobasic is a compound used in various medical applications.
What it treats
- pH adjustment in medical solutions
- buffering agent in pharmaceutical preparations
How it works
Monobasic helps maintain the right acidity or alkalinity in solutions, which is important for their effectiveness.
Who it's for
It is used for patients requiring specific pH levels in their treatments.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: monobasic
Monobasic is a term that can refer to various monobasic salts or compounds, which are typically used in biochemical and pharmaceutical contexts. Monobasic compounds can act as acid-base buffers, helping to maintain pH in biological systems. They can also be utilized in formulations to provide stability and enhance solubility.
Indications
- pH regulation in biological systems
- buffering agents in pharmaceutical formulations
- stabilizers in chemical reactions
Dosage
Children: Refer to specific monobasic compound guidelines for pediatric dosing information, as this varies widely based on the specific application and formulation.
Adults: Refer to specific monobasic compound guidelines for dosing information, as this varies widely based on the specific application and formulation.
Mechanism of action
Monobasic compounds, depending on their chemical nature, often act by dissociating into their respective ions in solution. This dissociation can influence the pH and ionic strength of the solution, which in turn can affect various biochemical reactions and cellular functions.
Pharmacodynamics
The pharmacodynamic effects of monobasic compounds are largely dependent on their specific chemical structure and the physiological context. Generally, they can modulate pH levels, affect enzyme activity, and influence ion transport across cell membranes. These compounds may also play a role in maintaining homeostasis in biological systems.
Pharmacokinetics
The pharmacokinetics of monobasic compounds can vary widely based on their formulation and route of administration. Typically, they are rapidly dissociated in biological fluids, allowing for immediate effects on pH and ionic balance. They may be absorbed systemically or act locally, depending on their intended use.
Pregnancy
Safety in pregnancy has not been established; use only if clearly needed.
Breast-feeding
Caution is advised; consult a healthcare professional before use.
Storage
Store in a cool, dry place, away from light and moisture.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.