Registered Kenya · PPB

DOXIMAR CAPSULES

DOXYCYCLIN HCL

12774 EACH CAPSULE CONTAINS DOXYCYCLIN HCL EQUIVALENT TO 100MG DOXYCYCLIN BASE GENERIC/BIOSIMILARS alimentary tract and metabolism

What it does

Doxycycline is an antibiotic that helps treat various infections by stopping the growth of bacteria.

Commonly used for: bacterial infections, acne, respiratory infections, urinary tract infections …

Read more in plain English ↓

Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

Ask about this medicine

Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.

Hard to find? We help patients in Kenya source rare medicines. We don't sell or dispense medicines - licensed pharmacies do.

Source this medicine

Registration & product details

Registration no.
12774
Registration date
-
Expiry date
-
Status
Registered
Active ingredient
DOXYCYCLIN HCL
Dosage form
EACH CAPSULE CONTAINS DOXYCYCLIN HCL EQUIVALENT TO 100MG DOXYCYCLIN BASE
Strength
-
Pack size
10 BLISTERS OF 10 CAPSULES PACKED IN A UNIT BOX WITH LITERATURE INSERT
Therapeutic class
GENERIC/BIOSIMILARS
ATC class (WHO)
A01AB - Antiinfectives and antiseptics for local oral treatment
Drug group
ALIMENTARY TRACT AND METABOLISM
RxNorm RxCUI
3640
Manufacturer / MAH
Biopharma
Applicant / LTR
BIOPHARMA LABORATORIES LTD
Country of origin
LOCAL
Manufacturer location
Building No. 01, Road 01 Dhaka Housing Main Rd, Dhaka 1207, Bangladesh

Source: Pharmacy and Poisons Board · fetched 2026-01-28 20:03:52 · updated 2026-08-03 03:13:09

Disclaimer: This information is sourced from Pharmacy and Poisons Board (Kenya). Always consult a qualified healthcare professional before using any medication.

About this medicine

Doxycycline is an antibiotic that helps treat various infections by stopping the growth of bacteria.

What it treats

  • bacterial infections
  • acne
  • respiratory infections
  • urinary tract infections
  • tick-borne diseases (like Lyme disease)

How it works

It works by preventing bacteria from producing proteins they need to grow and multiply.

Who it's for

Doxycycline is for adults and children who need treatment for certain bacterial infections.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: doxycyclin

BNF-referenced

Doxycycline is a broad-spectrum tetracycline antibiotic used to treat a variety of bacterial infections. It works by inhibiting protein synthesis in bacteria, leading to their growth inhibition and eventual death. Doxycycline is effective against both Gram-positive and Gram-negative bacteria, as well as atypical pathogens.

Indications

  • Respiratory tract infections
  • Skin infections
  • Acne
  • Sexually transmitted infections
  • Urinary tract infections
  • Periodontal disease
  • Preventing malaria
  • Anthrax
  • Rickettsial infections

Dosage

Children: Refer to the BNF for Children for specific dosing guidance.

Adults: Refer to the BNF for specific dosing guidance.

Mechanism of action

Doxycycline exerts its antibacterial effects by binding to the 30S ribosomal subunit of bacterial ribosomes. This binding interferes with the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis. This mechanism is effective against a wide range of microorganisms.

Pharmacodynamics

The pharmacodynamics of doxycycline include its bacteriostatic action, which inhibits the growth and reproduction of bacteria. Its activity is concentration-dependent, and it maintains efficacy against resistant strains through its unique mechanism of action. Doxycycline also has anti-inflammatory properties, which may be beneficial in treating certain conditions beyond infections.

Pharmacokinetics

Doxycycline is well absorbed from the gastrointestinal tract and reaches peak plasma concentrations within 2 to 4 hours post-administration. It is approximately 90-100% bioavailable when taken orally. The drug has a volume of distribution of about 0.7 L/kg and is highly protein-bound (approximately 90-93%). Doxycycline is metabolized in the liver and has a half-life of about 18-22 hours, allowing for once or twice daily dosing. It is excreted primarily in the urine, both as unchanged drug and metabolites.

Interactions

  • fosphenytoin + doxycycline: Moderate (decreases concentration)
  • rifampicin + doxycycline: Moderate (decreases exposure)
  • doxycycline + ciclosporin: Unknown (increases concentration)

Pregnancy

Doxycycline is contraindicated during pregnancy due to the risk of permanent discoloration of teeth and potential effects on fetal bone development.

Breast-feeding

Doxycycline is excreted in breast milk and may affect the infant's teeth and bones; caution is advised.

Storage

Store at room temperature, away from light and moisture. Keep out of reach of children.

Formulations

  • Capsules
  • Tablets
  • Oral Solution
PubChem / pathway

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Molecular reference: doxycyclin

PubChem CID 54671203

Molecular formula: C22H24N2O8

Biological pathways

Doxycycline Action Pathway PathBank Deregulating cellular metabolism through non-genotoxic carcinogens WikiPathways

Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.