Draxxin Injection
Tulathromycin
What it does
Tulathromycin is an antibiotic used to treat bacterial infections in animals. It helps to eliminate harmful bacteria and improve health.
Commonly used for: bacterial infections, respiratory infections
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Sourcing - Kenya onlyRegistration & product details
Source: Zambia Medicines Regulatory Authority · fetched 2026-07-09 03:39:45 · updated 2026-10-19 03:40:08
About this medicine
Tulathromycin is an antibiotic used to treat bacterial infections in animals. It helps to eliminate harmful bacteria and improve health.
What it treats
- bacterial infections
- respiratory infections
How it works
Tulathromycin works by stopping the growth of bacteria, helping the body's immune system to fight off the infection.
Who it's for
It is typically used in veterinary medicine for livestock and pets.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: tulathromycin
Tulathromycin is a macrolide antibiotic used primarily in veterinary medicine for the treatment of respiratory diseases in cattle and swine. It is a member of the triamilide class and is known for its long half-life, allowing for extended dosing intervals. Tulathromycin is effective against a variety of Gram-positive and some Gram-negative bacteria, particularly those associated with respiratory infections.
Indications
- Bovine respiratory disease
- Swine respiratory disease
- Mycoplasma infections
- Pasteurellosis
Dosage
Children: Refer to specific veterinary guidelines for dosing in young animals. Dosing may vary based on age, weight, and clinical condition.
Adults: Refer to specific veterinary guidelines for dosing in adult animals. Dosing is typically based on the weight of the animal and the severity of the infection.
Mechanism of action
Tulathromycin exerts its antibacterial effect by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit, preventing the peptide bond formation necessary for protein synthesis, thus ultimately leading to bacterial cell death. Its action is primarily bacteriostatic, although it can be bactericidal at higher concentrations.
Pharmacodynamics
Tulathromycin demonstrates a broad spectrum of activity against various pathogens, including Mycoplasma and Pasteurella species, which are commonly implicated in bovine and porcine respiratory diseases. The drug's pharmacodynamic profile is characterized by its ability to penetrate tissues effectively, providing high concentrations in the lungs and other respiratory tissues.
Pharmacokinetics
Tulathromycin is well absorbed following parenteral administration, with a long half-life that supports infrequent dosing schedules. It shows extensive tissue distribution, achieving significant concentrations in lung tissue and bronchial secretions. The drug is primarily eliminated via the liver, with minimal renal excretion, allowing for a favorable safety profile in animals with compromised kidney function.
Adverse effects
- Injection site reactions
- Diarrhea
- Nausea
- Vomiting
- Anorexia
Precautions
- Use with caution in animals with a history of hypersensitivity to macrolides
- Monitor for signs of gastrointestinal disturbances
Pregnancy
Not established in humans. Use only if the benefits outweigh the risks.
Breast-feeding
Not established in humans. Use with caution.
Storage
Store at room temperature, away from moisture and heat. Protect from light.
Formulations
- Injectable solution
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Molecular reference: tulathromycin
PubChem CID 9832301Molecular formula: C41H79N3O12
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.