Eliminate Liquid

Indications

• Control of agricultural pests
• Management of certain nematode infections

Dosage

Children: Refer to specific product guidelines for dosing.

Adults: Refer to specific product guidelines for dosing.

Mechanism of action

Abamectin works by stimulating the release of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the nervous system of invertebrates. This action leads to increased neuronal excitability, causing paralysis and death of the pests.

Pharmacodynamics

Abamectin exhibits potent insecticidal and acaricidal activity by disrupting neurological function in target pests. The increased GABA release inhibits normal nerve impulse transmission, resulting in paralysis. Its effectiveness can vary based on the pest species and environmental conditions.

Pharmacokinetics

The pharmacokinetics of abamectin involve absorption through the cuticle and gut of the target organisms. It has a relatively low systemic toxicity to mammals due to its limited ability to cross the blood-brain barrier. The compound is metabolized primarily in the liver and excreted in the feces, with a variable half-life depending on the species and conditions.

Pregnancy

There is limited information regarding the safety of abamectin in pregnancy. Caution is advised.

Breast-feeding

It is not known whether abamectin is excreted in human milk. Caution is advised.

Storage

Store in a cool, dry place, away from direct sunlight and out of reach of children.

Mechanism of action

Insecticide and acaricide with contact and stomach action. ... Acts by stimulating the release of gamma-aminobutyric acid, an inhibitory neurotransmitter, thus causing paralysis.