EPIROSA 1000MG CAPSULE
EVENING PRIMROSE OIL
What it does
Evening primrose oil is a natural supplement often used to support women's health and skin conditions.
Commonly used for: premenstrual syndrome (PMS), eczema, breast pain (mastalgia), menopausal symptoms
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:43 · updated 2026-09-29 04:33:06
About evening
Evening primrose oil is a natural supplement often used to support women's health and skin conditions.
What it treats
- premenstrual syndrome (PMS)
- eczema
- breast pain (mastalgia)
- menopausal symptoms
How it works
Evening primrose oil contains essential fatty acids that may help reduce inflammation and improve skin health.
Who it's for
Adults, particularly women experiencing PMS or skin issues.
Cautions
- • Consult a healthcare provider if you are pregnant, breastfeeding, or taking other medications.
- • May cause mild digestive upset in some people.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About primrose
Primrose is a plant-based supplement often used for various health conditions.
What it treats
- eczema (atopic dermatitis)
- premenstrual syndrome (PMS)
- menopausal symptoms
- rheumatoid arthritis
How it works
Primrose is thought to help improve skin health and relieve symptoms related to hormonal changes.
Who it's for
Primrose may be suitable for adults looking for natural remedies for skin issues or hormonal symptoms.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: evening
Evening primrose oil is derived from the seeds of the evening primrose plant (Oenothera biennis) and is commonly used as a dietary supplement. It contains gamma-linolenic acid (GLA), an omega-6 fatty acid that is believed to have anti-inflammatory properties. It is often used for conditions such as premenstrual syndrome (PMS), eczema, and rheumatoid arthritis, among others.
Indications
- Premenstrual syndrome (PMS)
- Eczema (atopic dermatitis)
- Rheumatoid arthritis
- Breast pain (mastalgia)
- Menopausal symptoms
Dosage
Children: Refer to established guidelines or consult a healthcare professional for appropriate dosing in children. Specific dosing recommendations are not well established.
Adults: Refer to established guidelines or consult a healthcare professional for appropriate dosing. Typical doses range from 500 mg to 3000 mg of evening primrose oil per day, depending on the condition being treated.
Mechanism of action
Evening primrose oil exerts its effects primarily through the presence of gamma-linolenic acid (GLA). GLA is converted in the body into prostaglandins, which are compounds that help regulate inflammation and other physiological processes. By increasing the levels of prostaglandins, GLA may help to alleviate symptoms associated with inflammation and hormonal imbalances.
Pharmacodynamics
The pharmacodynamic effects of evening primrose oil are attributed to its fatty acid composition, particularly GLA. It has been shown to modulate inflammatory responses, enhance skin barrier function, and may influence hormonal regulation, providing symptomatic relief in conditions like PMS and eczema. The anti-inflammatory effect may also contribute to its use in managing conditions like rheumatoid arthritis.
Pharmacokinetics
Evening primrose oil is absorbed in the gastrointestinal tract and metabolized by the liver. The bioavailability of GLA may vary among individuals and can be influenced by dietary factors. The half-life of GLA is not well-defined in the literature. The oil is generally well-tolerated, but gastrointestinal side effects may occur in some users.
Pregnancy
Limited data is available on the use of evening primrose oil during pregnancy. Caution is advised.
Breast-feeding
Evening primrose oil is generally considered safe during breastfeeding, but consult a healthcare provider for personalized advice.
Storage
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Clinical monograph: primrose
Primrose, commonly derived from the seeds of the evening primrose plant (Oenothera biennis), is primarily used as a dietary supplement. It is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid believed to have various health benefits, including anti-inflammatory properties. It is often marketed for conditions such as eczema, premenstrual syndrome (PMS), and rheumatoid arthritis.
Indications
- Eczema
- Premenstrual syndrome (PMS)
- Rheumatoid arthritis
- Menopausal symptoms
- Skin disorders
Dosage
Children: Refer to specific product guidelines, as dosages can vary based on formulation and indication.
Adults: Refer to specific product guidelines, as dosages can vary based on formulation and indication.
Mechanism of action
Gamma-linolenic acid (GLA) is metabolized to prostaglandin E1, which exerts anti-inflammatory effects. This pathway involves the conversion of GLA to dihomo-gamma-linolenic acid (DGLA), which is a precursor for the synthesis of anti-inflammatory prostaglandins, helping to modulate inflammatory responses in the body.
Pharmacodynamics
GLA is thought to alter the metabolism of arachidonic acid, leading to decreased production of pro-inflammatory eicosanoids. This can help alleviate symptoms associated with inflammatory conditions, and the fatty acids present in primrose may also contribute to skin barrier function and hydration, making it beneficial for skin-related disorders.
Pharmacokinetics
After oral administration, GLA is absorbed in the gastrointestinal tract, with peak plasma concentrations typically occurring within a few hours. It is then distributed throughout the body, where it can be incorporated into cell membranes. The metabolism of GLA involves conversion into various metabolites, including DGLA, and it is excreted mainly through urine and feces. The half-life of GLA can vary based on individual metabolism and dietary factors.
Adverse effects
- Gastrointestinal upset
- Nausea
- Diarrhea
- Headache
- Allergic skin reactions
Interactions
- May enhance the effects of anticoagulants
- May interact with antipsychotic medications
Precautions
- Use with caution in individuals with bleeding disorders
- Monitor for potential allergic reactions
Pregnancy
Safety during pregnancy has not been established. Consult a healthcare provider before use.
Breast-feeding
Safety during breastfeeding has not been established. Consult a healthcare provider before use.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Formulations
- Oil
- Capsules
- Tablets
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.
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