GARDASIL RECOMBINANT VACCINE INJECTION
QUADRIVALENT HUM.PAPILLOMAVIRUS 6,11,16,18
What it does
Quadrivalent vaccines help protect against four different strains of a virus, typically used to prevent certain diseases.
Commonly used for: prevention of influenza (flu), prevention of certain types of pneumonia
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Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:38 · updated 2026-09-19 04:30:21
About this medicine
Quadrivalent vaccines help protect against four different strains of a virus, typically used to prevent certain diseases.
What it treats
- prevention of influenza (flu)
- prevention of certain types of pneumonia
How it works
These vaccines stimulate the body's immune system to recognize and fight off specific viruses.
Who it's for
This vaccine is for individuals who need protection against multiple strains of the virus, including children and adults.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: quadrivalent
Quadrivalent vaccines are designed to protect against four different strains of a virus, commonly referring to the quadrivalent influenza vaccine which targets two influenza A strains and two influenza B strains. This type of vaccine is crucial in preventing seasonal influenza outbreaks and is especially important for high-risk populations.
Indications
- Prevention of influenza in adults and children
- Protection for high-risk groups, including the elderly and those with chronic health conditions
- Seasonal influenza vaccination campaigns
Dosage
Children: Refer to specific vaccination guidelines for children, with recommendations depending on age and previous vaccination history.
Adults: Refer to specific vaccination guidelines for adults, typically administered as a single dose per season.
Mechanism of action
Quadrivalent vaccines work by introducing inactivated or attenuated virus strains into the body, which stimulates the immune system to produce antibodies. These antibodies recognize and neutralize the virus upon subsequent exposure, thereby providing immunity against the targeted strains.
Pharmacodynamics
The pharmacodynamics of quadrivalent vaccines involve the activation of the adaptive immune response, leading to the production of specific antibodies against the influenza virus. This response typically peaks 2 to 4 weeks after vaccination, providing protective immunity. Vaccination not only reduces the risk of infection but also mitigates the severity of the disease in vaccinated individuals.
Pharmacokinetics
Quadrivalent vaccines are administered via intramuscular injection, leading to rapid absorption into the systemic circulation. The half-life of the immune response varies based on individual factors but generally provides immunity for several months. The vaccine components are processed by the immune system, with antibodies being produced and maintained in memory B cells for long-term protection.
Adverse effects
- Injection site reactions
- Fever
- Headache
- Fatigue
- Nausea
- Myalgia
Precautions
- Use with caution in individuals with a history of allergic reactions to vaccine components
- Monitor for any severe allergic reactions post-vaccination
- Consider underlying health conditions that may affect immune response
Pregnancy
Quadrivalent vaccines can be administered during pregnancy if the benefits outweigh the risks, especially during outbreaks or high-risk situations.
Breast-feeding
Safe to administer during breastfeeding.
Storage
Store in the refrigerator at 2°C to 8°C. Do not freeze. Protect from light.
Formulations
- Quadrivalent inactivated influenza vaccine
- Quadrivalent human papillomavirus vaccine
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.