ELOCOM OINTMENT
MONETASONE FUROATE
What it does
Monetasone is a medication used to treat inflammation and allergic reactions.
Commonly used for: inflammatory skin conditions (e.g., eczema, dermatitis), allergic reactions, conditions affecting the nose (e.g., rhinitis)
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Food and Drugs Authority · fetched 2026-04-18 08:32:58 · updated 2026-09-18 04:00:08
About this medicine
Monetasone is a medication used to treat inflammation and allergic reactions.
What it treats
- inflammatory skin conditions (e.g., eczema, dermatitis)
- allergic reactions
- conditions affecting the nose (e.g., rhinitis)
How it works
Monetasone reduces inflammation and helps relieve symptoms like redness and itching.
Who it's for
This medication is for adults and children who have inflammatory or allergic conditions.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: monetasone
Monetasone is a synthetic corticosteroid that exhibits anti-inflammatory and immunosuppressive properties. It is primarily used to manage various inflammatory conditions, including allergic reactions and autoimmune disorders. By mimicking the effects of hormones produced by the adrenal glands, monetasone helps to regulate the immune response and reduce inflammation.
Indications
- Allergic rhinitis
- Asthma
- Eczema
- Psoriasis
- Rheumatoid arthritis
- Inflammatory bowel disease
Dosage
Children: Refer to the BNF for Children for appropriate dosing information based on the child's age, weight, and specific condition.
Adults: Refer to established guidelines for specific dosing based on the condition being treated. Adjustments may be necessary based on clinical response and patient-specific factors.
Mechanism of action
Monetasone works by binding to corticosteroid receptors in the cytoplasm of target cells. This receptor-ligand complex translocates to the cell nucleus, where it regulates the transcription of genes involved in inflammation and immune response. It inhibits the production of pro-inflammatory cytokines, leading to a reduction in inflammatory processes.
Pharmacodynamics
Monetasone exhibits potent anti-inflammatory effects by decreasing the accumulation of inflammatory cells at the site of inflammation. It also suppresses the release of mediators involved in the inflammatory response, such as histamines and prostaglandins. The immunosuppressive action of monetasone helps in controlling autoimmune diseases and preventing transplant rejection.
Pharmacokinetics
Monetasone is well-absorbed when administered and has a high volume of distribution. The drug undergoes hepatic metabolism, primarily through cytochrome P450 enzymes. Its elimination half-life varies but is generally around several hours, with excretion primarily through the urine. The pharmacokinetic profile may vary based on the route of administration and the condition being treated.
Pregnancy
Monetasone should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consideration should be given to the specific clinical situation.
Breast-feeding
Monetasone is excreted in human milk, and caution should be exercised when administering to nursing mothers. The effects on the infant are not well studied.
Storage
Store at room temperature, away from moisture and heat. Keep out of reach of children.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.