FLORGUARD 10 POWDER (Each 100g contains Florfericol 10g
Florfericol 10g
What it does
Florfericol is an antibiotic used to treat certain infections caused by bacteria.
Commonly used for: bacterial infections, respiratory infections, skin infections
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Food and Drugs Authority · fetched 2026-07-10 04:00:14 · updated 2026-10-20 04:00:11
About this medicine
Florfericol is an antibiotic used to treat certain infections caused by bacteria.
What it treats
- bacterial infections
- respiratory infections
- skin infections
How it works
Florfericol works by stopping the growth of bacteria, helping the body to fight off the infection.
Who it's for
Florfericol is suitable for patients with bacterial infections as prescribed by a healthcare professional.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: florfericol
Florfericol is an antibiotic belonging to the class of phenicol antibiotics. It is primarily used in veterinary medicine for the treatment of bacterial infections in animals. It has a broad spectrum of activity against a variety of Gram-positive and Gram-negative bacteria. Florfericol's use in humans is limited and not well established, as it is mainly utilized in livestock and poultry to manage infections and promote growth.
Indications
- Bacterial infections
- Respiratory infections
- Skin and soft tissue infections
- Gastrointestinal infections
Dosage
Children: Refer to specific treatment guidelines and local protocols for dosing, as florfericol is not commonly used in human medicine.
Adults: Refer to specific treatment guidelines and local protocols for dosing, as florfericol is not commonly used in human medicine.
Mechanism of action
Florfericol exerts its antibacterial effect by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit, preventing the peptide bond formation during translation, which is essential for protein synthesis in bacteria. This mechanism leads to the cessation of bacterial growth and replication.
Pharmacodynamics
Florfericol has a bacteriostatic effect against a range of microorganisms. Its efficacy is influenced by factors such as the site of infection, bacterial susceptibility, and the presence of other medications. It demonstrates time-dependent activity, meaning that the duration of exposure to the drug is critical for its effectiveness.
Pharmacokinetics
Florfericol is absorbed following administration and distributes widely throughout the body tissues. It is metabolized primarily in the liver, and its elimination half-life can vary based on the route of administration and species. Renal excretion plays a role in its clearance, although specific pharmacokinetic parameters in humans are not well established due to limited use.
Adverse effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Rash
Precautions
- Use with caution in patients with liver impairment
- Monitor renal function during treatment
- Assess for potential hypersensitivity reactions
Pregnancy
Florfericol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus, as there are no adequate and well-controlled studies in pregnant women.
Breast-feeding
It is not known whether florfericol is excreted in human milk. Caution should be exercised when administering to nursing mothers.
Storage
Store at room temperature, away from moisture and heat. Keep out of reach of children.
Formulations
- Injectable solution
- Oral tablets
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.