NATURE'S WAY MSM TABLETS
METHYLSULFONYLMETHANE
What it does
Methylsulfonylmethane (MSM) is a natural compound often used to support joint health and reduce inflammation.
Commonly used for: joint pain, osteoarthritis, inflammation
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Food and Drugs Authority · fetched 2026-04-18 08:32:58 · updated 2026-10-20 04:00:06
About this medicine
Methylsulfonylmethane (MSM) is a natural compound often used to support joint health and reduce inflammation.
What it treats
- joint pain
- osteoarthritis
- inflammation
How it works
MSM is thought to help reduce pain and swelling in the body, particularly in the joints.
Who it's for
Adults looking for support with joint issues or inflammation.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: methylsulfonylmethane
BNF-referencedMethylsulfonylmethane (MSM) is an organosulfur compound that is widely used as a dietary supplement. It is believed to have anti-inflammatory properties and is commonly utilized for joint health, pain relief, and as a potential adjunct in the management of osteoarthritis and other inflammatory conditions. MSM is naturally found in some foods and is also produced in small amounts by the human body.
Indications
- Osteoarthritis
- Joint pain
- Inflammatory conditions
- Musculoskeletal disorders
Dosage
Children: Paediatric dosing information for methylsulfonylmethane is not well established. It is recommended to refer to the BNF for Children for guidance on the use and dosing in children.
Adults: The typical adult dosage of methylsulfonylmethane ranges from 1,500 mg to 6,000 mg daily, divided into two or three doses. It is advisable to refer to specific product guidelines or consult a healthcare professional for appropriate dosing.
Mechanism of action
The exact mechanism of action of methylsulfonylmethane is not fully understood. However, it is thought to exert its effects through the modulation of inflammatory processes and by providing sulfur, which is a vital component in the synthesis of collagen and other important biomolecules. MSM may also affect the permeability of cell membranes and influence the activity of various enzymes involved in inflammatory pathways.
Pharmacodynamics
Methylsulfonylmethane has been shown to have anti-inflammatory and analgesic properties, which may be mediated through its action on cytokines and other mediators of inflammation. It is thought to inhibit the production of pro-inflammatory cytokines, thereby reducing inflammation and pain associated with musculoskeletal conditions. The compound may also enhance antioxidant defenses and promote tissue repair.
Pharmacokinetics
Methylsulfonylmethane is well absorbed after oral administration, with peak plasma concentrations typically occurring within 1 to 2 hours. It is metabolized in the body through various pathways, including dimethyl sulfone degradation. The elimination half-life of MSM is not well established, but it is believed to be excreted primarily through the urine.
Pregnancy
There is insufficient reliable data on the safety of methylsulfonylmethane during pregnancy. Caution is advised.
Breast-feeding
It is not known whether methylsulfonylmethane is excreted in human milk. Caution is advised.
Storage
Store in a cool, dry place, away from direct sunlight and moisture.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Molecular reference: methylsulfonylmethane
PubChem CID 6213Molecular formula: C2H6O2S
Biological pathways
Source: PubChem (NCBI) · pathways from PathBank, Reactome, WikiPathways & PharmGKB.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.