NODIAR ORAL SUSPENSION POWDER
Disomectite
What it does
Disomectite is used to help treat gastrointestinal issues by absorbing toxins and reducing diarrhea.
Commonly used for: diarrhea, gastrointestinal disorders
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.
Sourcing - Kenya onlyRegistration & product details
Source: Food and Drugs Authority · fetched 2026-04-18 08:37:44 · updated 2026-10-23 04:00:14
About this medicine
Disomectite is used to help treat gastrointestinal issues by absorbing toxins and reducing diarrhea.
What it treats
- diarrhea
- gastrointestinal disorders
How it works
Disomectite works by binding to substances in the gut, which helps to reduce diarrhea and improve bowel movements.
Who it's for
Disomectite is suitable for adults and children experiencing diarrhea or related stomach issues.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: disomectite
Disomectite is a synthetic, high-purity, montmorillonite clay material used primarily as an antidiarrheal agent. It works by adsorbing toxins and pathogens in the gastrointestinal tract, thereby reducing the frequency of diarrhea. It is particularly useful in the management of acute diarrhea, including that caused by infections or toxins.
Indications
- Acute diarrhea
- Chronic diarrhea
- Diarrhea associated with gastrointestinal infections
- Toxin-induced diarrhea
Dosage
Children: Refer to specific guidelines or consult a healthcare professional for appropriate dosing.
Adults: Refer to specific guidelines or consult a healthcare professional for appropriate dosing.
Mechanism of action
Disomectite acts primarily through its adsorption properties. It binds to harmful substances, including bacteria, viruses, and toxins in the gastrointestinal tract, which helps to mitigate their effects and facilitates their elimination from the body. This mechanism reduces inflammation and irritation in the gut lining, helping to restore normal bowel function.
Pharmacodynamics
Disomectite exhibits properties of a bulk-forming agent as it absorbs water in the intestines, which increases stool bulk and consistency. This action not only alleviates diarrhea but also can provide a protective barrier in the gut, reducing further irritation from ingested irritants. Its non-systemic nature means that it does not enter the bloodstream and acts locally within the gastrointestinal tract.
Pharmacokinetics
Disomectite is not absorbed systemically; it remains in the gastrointestinal tract where it exerts its effects. Due to its high surface area and cation-exchange capacity, it effectively adsorbs various substances. The onset of action occurs within hours, and the duration of effect depends on the amount of substance to be adsorbed. As a result, it is crucial to maintain adequate hydration in patients using disomectite, especially if diarrhea persists.
Adverse effects
- Constipation
- Abdominal discomfort
- Nausea
Precautions
- Use with caution in patients with bowel obstruction
- Monitor for gastrointestinal symptoms
Pregnancy
Disomectite is generally considered safe for use during pregnancy, but it should be used only if clearly needed.
Breast-feeding
It is unknown whether disomectite is excreted in human milk. Caution is advised when administering to breastfeeding women.
Storage
Store in a cool, dry place away from direct sunlight.
Formulations
- Oral suspension
- Tablets
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.