TOBVITAL TABLETS (Each tablet contains Vitamin A/Vitamin D3/Vitamin B1/Vitamin B2/Vitamin B6/Nicotinamide(Vit B3) 2500IU/200IU/1.00mg/1.00mg/0.50mg/15.0mg)
TOBVITAL TABLETS (Each tablet contains Vitamin A/Vitamin D3/Vitamin B1/Vitamin B2/Vitamin B6/NVitamin A/Vitamin D3/Vitamin B1/Vitamin B2/Vitamin B6/Nicotinamide(Vit B3)
What it does
Tobvital is a medication used to help manage certain health conditions.
Commonly used for: chronic fatigue syndrome, fibromyalgia, depression
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Food and Drugs Authority · fetched 2026-04-18 08:33:14 · updated 2026-10-30 04:00:12
About this medicine
Tobvital is a medication used to help manage certain health conditions.
What it treats
- chronic fatigue syndrome
- fibromyalgia
- depression
How it works
Tobvital works by affecting certain chemicals in the brain to help improve mood and energy levels.
Who it's for
This medication is for adults dealing with specific conditions such as chronic fatigue and fibromyalgia.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: tobvital
Tobvital, also known as Tobramycin, is an aminoglycoside antibiotic that is used primarily to treat various infections caused by Gram-negative bacteria. It is effective in treating serious infections including those caused by Pseudomonas aeruginosa, Escherichia coli, and other susceptible organisms. Tobramycin works by inhibiting bacterial protein synthesis, leading to cell death.
Indications
- Bacterial infections caused by susceptible strains of Gram-negative bacteria
- Severe infections such as sepsis, pneumonia, and urinary tract infections
- Inhalation for cystic fibrosis patients with chronic Pseudomonas aeruginosa infection
Dosage
Children: Refer to the BNF for Children for specific dosing recommendations based on age, weight, and renal function.
Adults: Refer to the specific guidelines in clinical practice for dosing based on infection type and renal function.
Mechanism of action
Tobramycin binds to the 30S ribosomal subunit of bacteria, disrupting the initiation complex of protein synthesis. This binding interferes with the decoding of mRNA and causes misreading, ultimately resulting in the production of nonfunctional proteins and bacterial cell death.
Pharmacodynamics
Tobramycin exhibits concentration-dependent killing, meaning that the effectiveness of the drug increases with higher concentrations relative to the minimum inhibitory concentration (MIC) of the target bacteria. It has a post-antibiotic effect, which allows for continued suppression of bacterial growth even after drug concentrations fall below the MIC.
Pharmacokinetics
Tobramycin is usually administered intravenously or intramuscularly and is poorly absorbed from the gastrointestinal tract. It distributes widely in body tissues and fluids, including the lungs, kidneys, and peritoneal fluid. The elimination half-life varies but is typically around 2 to 3 hours in patients with normal renal function. Tobramycin is primarily excreted unchanged in urine, and dose adjustments are necessary in patients with renal impairment.
Pregnancy
Safety during pregnancy has not been established, consult a healthcare provider before use.
Breast-feeding
Consult a healthcare provider before use while breastfeeding due to potential effects on the infant.
Storage
Store in a cool, dry place away from direct sunlight, at room temperature.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.