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Vaccinium macrocarpon

FDA/SD.245-112212 Vaccinium macrocarpon 360mg

What it does

Macrocarpon is a natural ingredient often used for its potential health benefits.

Commonly used for: supporting urinary health, reducing inflammation, contributing to overall wellness

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Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Registration & product details

Registration no.
FDA/SD.245-112212
Registration date
2024-11-22
Expiry date
2029-12-01
Status
Valid
Active ingredient
Vaccinium macrocarpon
Dosage form
Vaccinium macrocarpon
Strength
360mg
Pack size
-
Therapeutic class
-
Applicant / LTR
Gokals laborex limited
Country of origin
Australia
Manufacturer location
37 Latitude Blvd, Thomastown VIC 3074, Australia

Source: Food and Drugs Authority · fetched 2026-04-18 08:32:59 · updated 2026-10-20 04:00:03

Disclaimer: This information is sourced from Food and Drugs Authority (Ghana). Always consult a qualified healthcare professional before using any medication.

About macrocarpon

Macrocarpon is a natural ingredient often used for its potential health benefits.

What it treats

  • supporting urinary health
  • reducing inflammation
  • contributing to overall wellness

How it works

Macrocarpon may help the body by providing antioxidants and supporting the immune system.

Who it's for

This ingredient is generally for individuals looking to enhance their urinary health and overall wellbeing.

Cautions

  • • Consult a healthcare provider before use, especially if pregnant, nursing, or taking other medications.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

About vaccinium

Vaccinium is a plant extract often used for its potential health benefits.

What it treats

  • urinary tract infections
  • diabetes management
  • antioxidant support

How it works

Vaccinium contains compounds that may help support urinary health and provide antioxidant effects.

Who it's for

This may be suitable for people looking to support urinary health or manage blood sugar levels.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: macrocarpon

Macrocarpon, commonly known as 'African locust bean' or 'Iru', is derived from the seeds of the Parkia biglobosa tree. It is traditionally used in various African cuisines and has been studied for its potential health benefits. The seeds are rich in protein, vitamins, and minerals, and are often used as a condiment or flavoring agent. In addition to its culinary uses, macrocarpon has been investigated for its potential medicinal properties, including antimicrobial, antioxidant, and anti-inflammatory effects.

Indications

  • Nutritional supplement
  • Culinary use
  • Antioxidant
  • Antimicrobial agent
  • Anti-inflammatory agent

Dosage

Children: Refer to established guidelines or consult a healthcare professional for appropriate dosing recommendations.

Adults: Refer to established guidelines or consult a healthcare professional for appropriate dosing recommendations.

Mechanism of action

The active components in macrocarpon, particularly the phytochemicals and compounds such as flavonoids, exhibit various biological activities. These compounds may function by scavenging free radicals, modulating enzyme activity, and influencing signaling pathways related to inflammation and immune responses. Some studies suggest that macrocarpon may enhance the activity of certain antibiotics, indicating a potential synergistic effect in antimicrobial therapy.

Pharmacodynamics

Macrocarpon displays a range of pharmacodynamic properties, including antioxidant activity, which helps to protect cells from oxidative stress, and antimicrobial activity, which can inhibit the growth of certain bacteria and fungi. Additionally, it may possess anti-inflammatory properties, potentially contributing to the reduction of symptoms associated with inflammation. The interaction of its bioactive compounds with various biological targets may lead to modulation of metabolic processes.

Pharmacokinetics

The pharmacokinetics of macrocarpon are not well-documented in the literature. However, it is known that the absorption of its bioactive compounds can vary based on their chemical nature, formulation, and the presence of other dietary components. Metabolism studies indicate that flavonoids and other phenolic compounds may undergo phase I and phase II metabolic processes, leading to various metabolites that can exert biological activity. The elimination pathways for these compounds generally involve renal excretion, although specific half-life data are not available.

Pregnancy

The safety of macrocarpon during pregnancy has not been established. It is advisable to consult a healthcare professional before use.

Breast-feeding

There is limited information available regarding the safety of macrocarpon during breastfeeding. Caution is recommended and a healthcare professional should be consulted.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

Clinical monograph: vaccinium

Vaccinium refers to a genus of flowering plants in the family Ericaceae, which includes various species such as blueberries, cranberries, and bilberries. These plants are known for their edible fruits, which are rich in vitamins, antioxidants, and phytochemicals. Vaccinium species have been studied for their potential health benefits, including anti-inflammatory and antioxidant effects, and are commonly used in dietary supplements and functional foods.

Indications

  • Antioxidant support
  • Prevention of urinary tract infections
  • Supporting cardiovascular health
  • Management of metabolic syndrome
  • Anti-inflammatory effects

Dosage

Children: Refer to specific product guidelines for dosage; ensure consultation with a healthcare provider for appropriate use in children.

Adults: Refer to specific product guidelines for dosage; generally used as part of a balanced diet or as a dietary supplement.

Mechanism of action

Vaccinium species exert their effects primarily through the presence of phenolic compounds, flavonoids, and anthocyanins. These bioactive compounds have been shown to scavenge free radicals, modulate inflammatory pathways, and influence metabolic processes. The anthocyanins in Vaccinium fruits can enhance endothelial function and improve insulin sensitivity, potentially benefiting cardiovascular health and glucose metabolism.

Pharmacodynamics

The pharmacodynamic effects of Vaccinium are attributed to its rich phytochemical composition. The antioxidants present help in reducing oxidative stress, which is implicated in various chronic diseases. Additionally, Vaccinium extracts may exhibit antimicrobial properties, which could contribute to their use in preventing urinary tract infections, particularly in cranberry products. The modulation of glucose metabolism and lipid profiles is also notable, with potential benefits in managing metabolic syndrome.

Pharmacokinetics

The pharmacokinetics of Vaccinium compounds can vary widely based on the specific species and preparation (fresh fruit, extract, etc.). Generally, bioactive compounds such as anthocyanins are rapidly absorbed in the gastrointestinal tract but may have variable bioavailability due to metabolic processes. The elimination half-life of these compounds can also differ, influenced by factors such as dietary habits and individual metabolism. Studies suggest that the consumption of Vaccinium can lead to increased levels of anthocyanins in plasma, although further research is needed to elucidate the pharmacokinetic profiles fully.

Adverse effects

  • Gastrointestinal upset
  • Allergic reactions
  • Headache

Precautions

  • Use with caution in patients with known allergies to Vaccinium species
  • Consult a healthcare provider before use in individuals with underlying health conditions

Pregnancy

Safety in pregnancy has not been established. Consult a healthcare provider before use.

Breast-feeding

Safety during breastfeeding has not been established. Consult a healthcare provider before use.

Storage

Store in a cool, dry place away from direct sunlight.

Formulations

  • Dried berries
  • Powdered extracts
  • Capsules
  • Tinctures

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.