What it does
Dinophosphate is a medication used to treat certain conditions related to phosphate metabolism.
Commonly used for: phosphate deficiency, metabolic bone disease
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Source: Zambia Medicines Regulatory Authority · fetched 2026-05-18 02:15:39 · updated 2026-10-19 03:40:25
About this medicine
Dinophosphate is a medication used to treat certain conditions related to phosphate metabolism.
What it treats
- phosphate deficiency
- metabolic bone disease
How it works
Dinophosphate helps to increase phosphate levels in the body, which is important for healthy bones and teeth.
Who it's for
This medication is for people who have low phosphate levels or conditions that affect phosphate metabolism.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: dinophosphate
Dinophosphate is an organophosphate compound primarily used as an herbicide. It functions by inhibiting certain enzymes involved in the metabolism of plants, leading to their death. Dinophosphate may also have applications in pest control due to its neurotoxic effects on insects. Its use is generally regulated due to potential environmental and health impacts.
Indications
- Herbicide for agricultural use
- Pest control in horticulture
Dosage
Children: Refer to product-specific guidelines and local regulations for appropriate dosing and application methods.
Adults: Refer to product-specific guidelines and local regulations for appropriate dosing and application methods.
Mechanism of action
Dinophosphate acts as a cholinesterase inhibitor. By inhibiting the enzyme acetylcholinesterase, it prevents the breakdown of acetylcholine in the synaptic cleft, leading to an accumulation of acetylcholine. This results in prolonged stimulation of cholinergic receptors, affecting both the central and peripheral nervous systems. The ultimate effect is the disruption of normal neurotransmission, which can lead to paralysis in pests and undesirable plant growth.
Pharmacodynamics
The pharmacodynamic effects of dinophosphate are primarily linked to its role as an acetylcholinesterase inhibitor. Increased levels of acetylcholine enhance stimulation of both muscarinic and nicotinic receptors. This can lead to symptoms such as muscle twitching, respiratory distress, and in severe cases, paralysis. In plants, the inhibition of metabolic processes leads to herbicidal activity, causing wilting and death of the plant.
Pharmacokinetics
The pharmacokinetics of dinophosphate involves absorption, distribution, metabolism, and excretion that can vary based on formulation and mode of application. Following application, it is absorbed through plant tissues and can be distributed throughout the plant systemically. The compound is subject to rapid degradation in the environment, which limits its persistence. Metabolic pathways typically involve hydrolysis and conjugation, leading to various breakdown products, some of which may still exhibit biological activity.
Pregnancy
The safety of dinophosphate during pregnancy has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus.
Breast-feeding
It is not known whether dinophosphate is excreted in human milk. Caution should be exercised when administering to nursing mothers.
Storage
Store at room temperature, away from moisture and heat. Keep the container tightly closed.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.