International reference: 2 US FDA recalls for this ingredient
Labeling: Incorrect or Missing Lot and/or Exp Date: Incorrect expiration date on label (grapevine)
Labeling Not Elsewhere Classified: Misbranding. (grapevine)
US-market enforcement records (OpenFDA), shown for reference - not specific to this product in Malawi.
What it does
This medicine is an extract that is used for various health conditions.
Commonly used for: general health improvement, nutritional support
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
Ask about this medicine
Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.
Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.
Sourcing - Kenya onlyRegistration & product details
Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:42 · updated 2026-09-29 04:33:05
About extract
This medicine is an extract that is used for various health conditions.
What it treats
- general health improvement
- nutritional support
How it works
The extract may provide health benefits by supplying essential nutrients or compounds that support bodily functions.
Who it's for
This medicine is suitable for individuals looking to improve their overall health or address specific nutritional needs.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About grapevine
Grapevine is a natural product that may have health benefits.
What it treats
- antioxidant support
- heart health
- blood circulation improvement
How it works
Grapevine contains compounds that may help protect cells and improve blood flow.
Who it's for
People looking for natural support for heart health and circulation.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: extract
Extracts are concentrated preparations obtained from plants, herbs, or other natural sources through various extraction methods such as solvent extraction, steam distillation, or cold pressing. They are used for their therapeutic properties in herbal medicine and can contain a variety of bioactive compounds including alkaloids, flavonoids, terpenes, and essential oils. The specific effects and uses of an extract depend on its source material and the compounds it contains.
Indications
- General wellness support
- Anti-inflammatory effects
- Antioxidant activity
- Digestive aid
- Support for immune function
Dosage
Children: Paediatric dosing should be determined based on the specific extract and its intended use. Consultation with a healthcare provider is recommended for accurate dosing.
Adults: Dosage varies widely depending on the specific extract and formulation. It is essential to follow the manufacturer's instructions or consult a healthcare professional for appropriate dosing.
Mechanism of action
The mechanism of action of herbal extracts can vary significantly based on their constituents. Commonly, they exert their effects through multiple pathways including modulation of neurotransmitter systems, interference with inflammatory processes, or direct antioxidant activity. Some extracts may activate certain receptors or inhibit enzymes related to disease processes.
Pharmacodynamics
The pharmacodynamics of extracts is complex due to the presence of multiple active compounds which can have synergistic or antagonistic effects. These compounds may influence cellular signaling pathways, alter gene expression, or modulate immune response. The overall pharmacological profile is determined by the specific composition of the extract, its concentration, and the biological target it interacts with.
Pharmacokinetics
The pharmacokinetics of extracts involves absorption, distribution, metabolism, and excretion of the active compounds. Generally, herbal extracts are absorbed in the gastrointestinal tract, with bioavailability influenced by factors such as formulation, the presence of food, and individual metabolic differences. Compounds may undergo hepatic metabolism, and elimination can occur through urine or feces, depending on their chemical nature.
Pregnancy
Consult a healthcare professional before use, as the safety of the extract during pregnancy has not been established.
Breast-feeding
Consult a healthcare professional before use, as the safety of the extract during breastfeeding has not been established.
Storage
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
Clinical monograph: grapevine
Grapevine, particularly the plant Vitis vinifera, is widely recognized for its health benefits, primarily due to its bioactive compounds such as resveratrol, flavonoids, and polyphenols. These compounds are known for their antioxidant, anti-inflammatory, and cardiovascular protective effects. Grapevine extracts and products derived from grapes are often used in complementary and alternative medicine, as well as in dietary supplements.
Indications
- Antioxidant support
- Cardiovascular health
- Anti-inflammatory purposes
- Potential anti-cancer properties
- Support for metabolic syndrome
Dosage
Children: Refer to specific product guidelines as dosages may vary based on formulation and intended use.
Adults: Refer to specific product guidelines as dosages may vary based on formulation and intended use.
Mechanism of action
The major active compound in grapevine, resveratrol, exerts its effects through multiple pathways, including the activation of sirtuins, which are proteins that regulate cellular processes including aging and inflammation. Resveratrol also modulates signaling pathways related to oxidative stress and inflammation, notably inhibiting NF-kB and activating the AMPK pathway, leading to improved metabolic health and reduced inflammation.
Pharmacodynamics
The pharmacodynamic effects of grapevine extracts are largely attributed to their antioxidant properties, which help to neutralize free radicals and reduce oxidative stress. Additionally, these extracts may enhance endothelial function, promote vasodilation, and improve lipid profiles, thus contributing to cardiovascular health. The anti-inflammatory properties of grapevine compounds can also influence various chronic conditions linked to inflammation.
Pharmacokinetics
Grapevine compounds, particularly resveratrol, exhibit variable absorption, distribution, metabolism, and excretion (ADME) characteristics. Resveratrol is rapidly absorbed in the gastrointestinal tract but undergoes extensive first-pass metabolism, resulting in lower systemic bioavailability. The half-life of resveratrol is relatively short, around 1 to 2 hours, necessitating multiple doses for sustained effect. Metabolites of resveratrol are primarily excreted through urine.
Pregnancy
Limited data available. Consult healthcare provider before use.
Breast-feeding
Consult healthcare provider before use, as safety during breastfeeding is not well established.
Storage
Store in a cool, dry place away from direct sunlight.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.
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