Registered Malawi · PMRA

GRIPE WATER COMBINATION PRODUCT LIQUID

GRIPE WATER

PMPB/PL143/55 LIQUID

What it does

Gripe is used to relieve discomfort from gas and bloating in the stomach and intestines.

Commonly used for: gas pain, bloating, colic in infants

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Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.

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Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.

Sourcing - Kenya only

Registration & product details

Registration no.
PMPB/PL143/55
Registration date
16/04/2010
Expiry date
30/06/2011
Status
Registered
Active ingredient
GRIPE WATER
Dosage form
LIQUID
Strength
-
Pack size
-
Therapeutic class
-
Manufacturer / MAH
-
Applicant / LTR
-
Country of origin
-

Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:38 · updated 2026-09-22 04:33:02

Disclaimer: This information is sourced from Pharmacy and Medicines Regulatory Authority (Malawi). Always consult a qualified healthcare professional before using any medication.

About this medicine

Gripe is used to relieve discomfort from gas and bloating in the stomach and intestines.

What it treats

  • gas pain
  • bloating
  • colic in infants

How it works

Gripe helps to break down gas bubbles in the gut, making it easier for gas to pass and relieving discomfort.

Who it's for

Gripe is suitable for adults and children, including infants, who experience gas-related discomfort.

AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.

Clinical monograph: gripe

Gripe water is a liquid supplement traditionally used to relieve colic, gas, and other gastrointestinal discomforts in infants. It typically contains a combination of herbal ingredients, such as fennel and ginger, along with sodium bicarbonate to ease stomach upset. The formulation is often alcohol-free and may vary by manufacturer.

Indications

  • Colic
  • Gastrointestinal gas
  • Bloating
  • Stomach upset

Dosage

Children: Refer to the specific product instructions and consult a healthcare professional for appropriate dosing in infants.

Mechanism of action

The herbal components of gripe water, such as fennel and ginger, are thought to possess carminative properties, which help to reduce gas and bloating in the gastrointestinal tract. Sodium bicarbonate neutralizes stomach acid, providing additional relief from discomfort.

Pharmacodynamics

Gripe water's effects are primarily due to its herbal constituents. Fennel has been shown to relax the muscles in the gastrointestinal tract, aiding in the expulsion of gas. Ginger may enhance digestive function and reduce nausea. The combination of these ingredients can improve gastrointestinal motility and relieve discomfort in infants.

Pharmacokinetics

The pharmacokinetics of gripe water are not well-studied due to its herbal composition and the variability in formulations. Generally, herbal ingredients are absorbed in the gastrointestinal tract, with their effects being rapid but transient, especially in infants. The elimination half-life of herbal compounds can vary widely depending on the specific ingredient and the individual infant's metabolism.

Adverse effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort
  • Allergic reactions

Precautions

  • Use with caution in patients with known allergies to herbal components
  • Consider potential interactions with other medications

Pregnancy

Consult with a healthcare provider before use, as safety during pregnancy is not well established.

Breast-feeding

Consult with a healthcare provider before use, as safety during breastfeeding is not well established.

Storage

Store in a cool, dry place away from direct sunlight. Keep out of reach of children.

Formulations

  • Liquid
  • Capsules
  • Tablets
  • Tea

AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.

This drug in other countries

The same active ingredient registered across other registries we cover - including different brands.