What it does
Alb is a medication used to treat infections caused by certain parasites.
Commonly used for: intestinal worm infections, hookworm disease, strongyloidiasis
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 21:16:22 · updated 2026-07-20 08:59:33
About alb
Alb is a medication used to treat infections caused by certain parasites.
What it treats
- intestinal worm infections
- hookworm disease
- strongyloidiasis
How it works
Alb works by killing the parasites in the body, helping to eliminate the infection.
Who it's for
Alb is for people diagnosed with parasitic infections, especially those affecting the intestines.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
About endazole
Endazole is a medication used to treat various infections caused by parasites.
What it treats
- intestinal worms (helminthiasis)
- some types of skin infections
How it works
Endazole works by killing the parasites or preventing them from growing and multiplying in the body.
Who it's for
Endazole is for people suffering from infections due to parasites.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: endazole
Endazole is an anthelmintic medication primarily used to treat parasitic infections caused by intestinal worms. It functions by inhibiting the metabolism of the parasites, leading to their death. Endazole is utilized in managing conditions such as ascariasis, hookworm infection, and other helminthic diseases.
Indications
- Ascariasis
- Hookworm infection
- Strongyloidiasis
- Enterobiasis
- Trichuriasis
Dosage
Children: Refer to the BNF for Children for specific dosing information.
Adults: Refer to the BNF for specific dosing information.
Mechanism of action
Endazole works by disrupting the energy metabolism of helminths. It inhibits the enzyme fumarate reductase, which is critical for the energy production in parasites. This disruption leads to a depletion of ATP levels in the parasites, ultimately resulting in their death.
Pharmacodynamics
Endazole has a selective action on the parasitic cells while sparing host cells. The drug's efficacy is closely related to its ability to inhibit critical metabolic pathways in the parasites, which are not present in mammalian cells. This selectivity reduces potential adverse effects on the host, making it a well-tolerated option for the treatment of helminthic infections.
Pharmacokinetics
Endazole is absorbed in the gastrointestinal tract and undergoes hepatic metabolism. Its half-life varies depending on the formulation and the specific parasite being treated. The drug is excreted primarily through the urine, with some metabolites appearing in the faeces. Food intake can influence its bioavailability, and it is often recommended to administer it with food to enhance absorption.
Pregnancy
Endazole should only be used during pregnancy if the potential benefit justifies the potential risk to the fetus.
Breast-feeding
It is unknown whether endazole is excreted in human milk. Caution should be exercised when administering to nursing mothers.
Storage
Store at room temperature, away from light and moisture. Keep out of reach of children.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.