Iva Super Injection
Chlorsulon 100 mg/ml
What it does
Chlorsulon is a medication used to treat certain parasitic infections in animals. It helps eliminate specific types of worms.
Commonly used for: parasitic infections (helminthiasis)
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Sourcing - Kenya onlyRegistration & product details
Source: Zambia Medicines Regulatory Authority · fetched 2026-03-12 00:07:03 · updated 2026-10-19 03:39:23
About this medicine
Chlorsulon is a medication used to treat certain parasitic infections in animals. It helps eliminate specific types of worms.
What it treats
- parasitic infections (helminthiasis)
How it works
Chlorsulon works by interfering with the metabolism of parasites, leading to their death.
Who it's for
This medication is typically used in veterinary medicine for treating infections in livestock.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: chlorsulon
Chlorsulon is an anthelmintic agent primarily used in veterinary medicine, particularly for the treatment of liver fluke infections in livestock. It works by inhibiting specific metabolic pathways in parasites, leading to their death. Chlorsulon is often used in combination with other anthelmintics to enhance efficacy against various parasitic infections.
Indications
- Liver fluke infections
- Fascioliasis
- Other trematode infections
Dosage
Children: Refer to local guidelines or veterinary recommendations for appropriate dosing regimens.
Adults: Refer to local guidelines or veterinary recommendations for appropriate dosing regimens.
Mechanism of action
Chlorsulon acts as a selective inhibitor of the enzyme phosphofructokinase, which is crucial for the glycolytic pathway in helminths. By disrupting glucose metabolism, chlorsulon deprives the parasites of energy, ultimately leading to their death. It may also affect other metabolic processes, contributing to its anthelmintic action.
Pharmacodynamics
Chlorsulon displays a selective toxicity towards certain helminths while being largely non-toxic to mammals. Its effectiveness is based on its ability to interfere with the energy production of parasites, particularly those that rely heavily on anaerobic metabolism. The drug's action is enhanced when used in conjunction with other anthelmintics, as it targets different metabolic pathways.
Pharmacokinetics
Chlorsulon is absorbed from the gastrointestinal tract when administered orally. Its pharmacokinetic profile includes a relatively short half-life, necessitating multiple doses for optimal efficacy. The drug is primarily excreted via the urine, and its metabolites may also contribute to its anthelmintic activity. The distribution of chlorsulon in tissues is limited, which reduces the potential for toxicity in non-target species.
Adverse effects
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Anorexia
- Liver enzyme elevation
- Allergic reactions
Precautions
- Use with caution in patients with liver impairment
- Monitor liver function during treatment
- Not recommended for use in pregnant or breastfeeding women
Pregnancy
Chlorsulon is not recommended for use during pregnancy due to lack of sufficient safety data.
Breast-feeding
Chlorsulon is not recommended for use while breastfeeding due to insufficient safety data.
Storage
Store at room temperature, away from light and moisture.
Formulations
- Oral tablets
- Injectable solution
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.
This drug in other countries
The same active ingredient registered across other registries we cover - including different brands.
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