MOSPEL MOSQUITO REPELLENT (S) 250MG/ML(25%W/W) CREAM
N,N-DIETHYL-3-TOLUAMIDE
What it does
N-diethyl-3-toluamide is a substance commonly used to repel insects and protect against bites.
Commonly used for: insect repellent, protection against mosquito bites, prevention of tick bites
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Sourcing - Kenya onlyRegistration & product details
Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:38 · updated 2026-09-29 04:33:03
About this medicine
N-diethyl-3-toluamide is a substance commonly used to repel insects and protect against bites.
What it treats
- insect repellent
- protection against mosquito bites
- prevention of tick bites
How it works
It works by masking scents that attract insects, making it harder for them to find you.
Who it's for
It is suitable for people who need protection from insect bites, such as those spending time outdoors.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: ndiethyl3toluamide
Diethyl toluamide (DEET) is a widely used insect repellent, primarily effective against mosquitoes, ticks, and other biting insects. It was developed in 1957 and has become the most common active ingredient in insect repellents worldwide. DEET works by masking the scents that attract insects to humans, thereby preventing bites and the transmission of insect-borne diseases.
Indications
- Prevention of insect bites
- Protection against mosquito-borne diseases such as malaria and dengue fever
- Protection against ticks and associated diseases such as Lyme disease
Dosage
Children: For children, use a lower concentration formulation and apply sparingly to exposed skin, avoiding hands, eyes, and mouth. Follow specific product guidelines for age and concentration.
Adults: Apply uniformly to exposed skin or clothing, avoiding eyes and mouth. Reapply as needed, especially after swimming or sweating.
Mechanism of action
DEET's exact mechanism of action is not completely understood, but it is believed to interfere with the insect's ability to detect odors. It is thought to alter the function of odorant receptors in insects, which diminishes their ability to recognize and respond to human body odors and carbon dioxide, both of which attract them.
Pharmacodynamics
DEET has a long duration of action, providing effective protection against insect bites for several hours after application. It is primarily applied topically and is absorbed into the skin, where it can exert its repellent effects. The effectiveness can vary based on the concentration of DEET in the formulation, with higher concentrations generally providing longer-lasting protection.
Pharmacokinetics
DEET is absorbed through the skin and can be detected in the bloodstream after application. It has a rapid onset of action, typically providing immediate protection upon application. The distribution in body tissues is not extensively documented, but it is known to be metabolized in the liver and excreted via urine. The half-life of DEET varies, but it generally remains in the system for several hours, depending on the formulation and method of application.
Adverse effects
- Skin irritation
- Allergic reactions
- Respiratory issues
- Nausea
- Headaches
Precautions
- Avoid contact with eyes and mouth
- Use with caution in individuals with sensitive skin
- Not recommended for use in infants under 2 months of age
Pregnancy
Use only if the benefits outweigh the risks, as safety during pregnancy is not fully established.
Breast-feeding
Use with caution, as it may be excreted in breast milk.
Storage
Store in a cool, dry place away from direct sunlight and heat. Keep out of reach of children.
Formulations
- Topical solution
- Lotion
- Spray
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.