MOSPEL MOSQUITO REPELLENT (S) 300MG/ML (30%) LUQUID
N,N-DIETHYLTOLUAMIDE
What it does
N-diethyltoluamide is a chemical used mainly as an insect repellent to protect against bites from mosquitoes and other insects.
Commonly used for: insect repellent
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Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:38 · updated 2026-09-29 04:33:03
About this medicine
N-diethyltoluamide is a chemical used mainly as an insect repellent to protect against bites from mosquitoes and other insects.
What it treats
- insect repellent
How it works
It works by masking the scents that attract insects, making it harder for them to find and bite you.
Who it's for
It is suitable for individuals looking to prevent insect bites, especially in areas where insect-borne diseases are common.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: ndiethyltoluamide
N,N-Diethyl-meta-toluamide, commonly known as DEET, is an insect repellent widely used to prevent mosquito and tick bites. It is effective against a variety of arthropods and is available in various formulations including sprays, lotions, and wipes. DEET works primarily by interfering with the insect's sense of smell, making it difficult for them to locate humans and animals.
Indications
- Prevention of insect bites
- Protection against mosquito-borne diseases such as malaria and dengue fever
- Protection against tick bites that may transmit Lyme disease
Dosage
Children: For children, use products with lower concentrations (10% to 30% DEET), applying sparingly to exposed skin. Avoid application to hands, eyes, and mouth, and do not apply to children under 2 months of age.
Adults: Apply a thin layer of DEET to exposed skin, using products with concentrations ranging from 10% to 30%. Follow product-specific instructions for reapplication and duration of protection.
Mechanism of action
DEET is believed to work by inhibiting the function of odorant receptors in insects, which affects their ability to detect the presence of humans and animals. Specifically, it alters the behavior of sensory neurons that are responsible for detecting carbon dioxide and lactic acid, substances that are typically emitted by humans and attract mosquitoes.
Pharmacodynamics
DEET's effectiveness as an insect repellent is dose-dependent. Higher concentrations provide longer-lasting protection but may also increase the risk of skin irritation. DEET does not kill insects but rather repels them, reducing the likelihood of bites and transmission of vector-borne diseases.
Pharmacokinetics
When applied to the skin, DEET is absorbed and can reach systemic circulation. However, its absorption rate varies based on the formulation and concentration used. DEET is metabolized primarily in the liver, and its metabolites are excreted in urine. The half-life of DEET in humans is not well established but is thought to vary based on the formulation and application method.
Adverse effects
- Skin irritation or rash
- Allergic reactions
- Eye irritation
- Respiratory issues (inhalation of aerosolized product)
- Headaches
- Nausea
Precautions
- Avoid application to broken or irritated skin.
- Use with caution in individuals with a history of skin sensitivities.
- Keep away from eyes and mouth, as it may cause irritation.
- Wash hands thoroughly after application to avoid unintentional exposure.
Pregnancy
Considered safe for use during pregnancy; however, it is advisable to consult healthcare providers before use.
Breast-feeding
Generally considered safe for breastfeeding mothers, but it is recommended to apply carefully to avoid contact with the infant.
Storage
Store in a cool, dry place away from direct sunlight and heat. Keep out of reach of children.
Formulations
- Topical cream
- Liquid spray
- Aerosol spray
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.