What it does
Cabocisteine is a medication used to help relieve symptoms of cough and reduce mucus in the airways.
Commonly used for: cough, excess mucus in the lungs
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
Ask about this medicine
Answers come only from this medicine's registration record, BNF monograph and interaction data - not medical advice.
Medicine sourcing is available in Kenya only. We don't sell or dispense medicines - licensed pharmacies do.
Sourcing - Kenya onlyRegistration & product details
Source: Pharmacy and Medicines Regulatory Authority · fetched 2026-04-21 17:37:38 · updated 2026-09-29 04:33:03
About this medicine
Cabocisteine is a medication used to help relieve symptoms of cough and reduce mucus in the airways.
What it treats
- cough
- excess mucus in the lungs
How it works
It works by thinning the mucus, making it easier to cough up and clear from the airways.
Who it's for
Cabocisteine is generally used for adults and children who have a cough with thick mucus.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: cabocisteine
Cabocisteine is a mucolytic agent primarily used to reduce the viscosity of mucus in respiratory conditions. It acts by altering the structure of mucus, making it easier to expel. This drug is particularly beneficial in conditions characterized by excessive mucus production, such as chronic bronchitis and cystic fibrosis.
Indications
- Chronic bronchitis
- Cystic fibrosis
- Asthma (for mucus management)
- Chronic obstructive pulmonary disease (COPD)
Dosage
Children: Paediatric dosing must be evaluated based on age and weight. Refer to the BNF for Children for appropriate dosing guidance.
Adults: The specific adult dosage should be determined based on clinical guidelines and patient needs. Refer to local prescribing information for detailed dosing recommendations.
Mechanism of action
Cabocisteine works by breaking down the disulfide bonds in mucoproteins, leading to a reduction in mucus viscosity. This action facilitates easier expectoration and clearance of mucus from the airways, improving respiratory function.
Pharmacodynamics
Cabocisteine exhibits mucolytic activity, which helps in thinning and loosening mucus in the airways. This can enhance the effectiveness of cough reflex and improve overall lung function, especially in patients suffering from chronic respiratory diseases. It may also have some anti-inflammatory properties, contributing to its therapeutic effects in respiratory conditions.
Pharmacokinetics
Cabocisteine is generally well absorbed after oral administration. It undergoes hepatic metabolism and is excreted primarily via the renal route. The drug has a half-life that allows for once or twice daily dosing, depending on the specific clinical scenario. The onset of action is typically within a few hours, with peak effects observed within a day.
Contra-indications
- Hypersensitivity to cabocisteine or any of its components
- Severe renal impairment
Adverse effects
- Gastrointestinal disturbances (nausea, vomiting, diarrhea)
- Headache
- Dizziness
- Rash
- Dry mouth
Precautions
- Use with caution in patients with renal impairment
- Monitor for gastrointestinal side effects in patients with a history of gastrointestinal disorders
Pregnancy
There is limited data on the use of cabocisteine during pregnancy. Consult a healthcare professional before use.
Breast-feeding
Cabocisteine is excreted in breast milk. Caution is advised when administering to nursing mothers.
Storage
Store at room temperature, away from light and moisture. Keep out of reach of children.
Formulations
- Capsules
- Syrup
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.