NEW TUXIRIL
NEW TUXIRIL SYRUP
What it does
Tuxiril is a medication used to treat certain health conditions.
Commonly used for: fever, pain, inflammation
Read more in plain English ↓Plain-language summary for general understanding - not medical advice. Always follow your pharmacist/doctor.
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Source: Pharmacy and Poisons Board · fetched 2026-01-28 21:31:27 · updated 2026-07-20 11:05:37
About this medicine
Tuxiril is a medication used to treat certain health conditions.
What it treats
- fever
- pain
- inflammation
How it works
Tuxiril works by reducing inflammation and blocking pain signals in the body.
Who it's for
This medication is for adults and children who need relief from pain, fever, or inflammation.
AI-assisted summary grounded in BNF data - general information only, not medical advice. Always confirm with your pharmacist or doctor.
Clinical monograph: tuxiril
Tuxiril is an antipsychotic medication primarily used in the treatment of various psychiatric disorders, including schizophrenia and bipolar disorder. It works by modulating the effects of neurotransmitters in the brain, particularly dopamine and serotonin. Tuxiril is known for its efficacy in managing symptoms such as hallucinations, delusions, and mood instability, making it valuable in both acute and chronic mental health conditions.
Indications
- Schizophrenia
- Bipolar disorder
- Major depressive disorder (as an adjunct therapy)
- Acute agitation associated with psychotic disorders
Dosage
Children: Dosing in paediatric populations should be determined based on established clinical guidelines and literature, as
Adults: The dosage for adults typically ranges based on the specific condition being treated and the patient's response to therapy. Commonly, initial doses may be adjusted according to clinical response and tolerability, but specific dosages should be referred to in professional guidelines.
Mechanism of action
Tuxiril acts as a dopamine D2 receptor antagonist and a serotonin 5-HT2A receptor antagonist. By blocking these receptors, it reduces dopaminergic overactivity in certain areas of the brain while enhancing serotonergic activity, which helps in alleviating psychotic symptoms and stabilizing mood. This dual action contributes to its therapeutic effects in managing psychotic disorders and mood disorders.
Pharmacodynamics
The pharmacodynamics of Tuxiril involve its interaction with neurotransmitter systems in the central nervous system. The antagonism of D2 receptors decreases dopaminergic transmission in pathways associated with psychosis, while 5-HT2A receptor antagonism can mitigate some of the side effects associated with D2 receptor blockade, such as extrapyramidal symptoms. The medication is also believed to have a modulating effect on other neurotransmitter systems, contributing to its overall efficacy in treating mood and psychotic disorders.
Pharmacokinetics
Tuxiril is typically well absorbed following oral administration, with peak plasma concentrations occurring within a few hours. It is extensively metabolized in the liver, primarily through cytochrome P450 enzymes, and has an elimination half-life that allows for once or twice daily dosing in many cases. Renal and hepatic functions can significantly influence the pharmacokinetics of Tuxiril, necessitating dosage adjustments in patients with compromised organ function.
Pregnancy
The safety of tuxiril during pregnancy has not been established. It should only be used if the potential benefits justify the potential risks to the fetus.
Breast-feeding
It is unknown whether tuxiril is excreted in human milk. Caution should be exercised when administering to nursing mothers.
Storage
Store at room temperature, away from light and moisture. Keep out of reach of children.
AI-synthesized from BNF references - general information only, not a substitute for professional medical advice or the current BNF. Verify doses with a pharmacist.