OSEX CAPSULES

Indications

• Bone defects
• Osteoporosis
• Dental implants
• Bone grafting
• Maxillofacial surgery

Dosage

Children: Refer to specific guidelines for paediatric applications, as dosage can vary significantly based on age and condition.

Adults: Dosage varies based on specific formulation and clinical application; refer to product-specific guidelines.

Mechanism of action

Hydroxyapatite facilitates bone repair and regeneration by providing a scaffold for new bone formation. It promotes osteoblast activity and serves as a reservoir for calcium and phosphate ions, essential for mineralization processes in bone tissue.

Pharmacodynamics

Hydroxyapatite exhibits osteoconductive properties, allowing for the formation of new bone tissue around it. It enhances the mineralization process, which is crucial for the strength and stability of the newly formed bone. Its chemical structure closely resembles that of natural bone, promoting better integration and healing.

Pharmacokinetics

Hydroxyapatite is not absorbed in the traditional sense as it is used primarily as a biomaterial. It remains at the site of implantation and gradually gets integrated into the host bone. Its degradation and resorption rates vary depending on the specific formulation and application but are generally slow, allowing for sustained support during the healing process.

Pregnancy

There are no adequate and well-controlled studies in pregnant women. Hydroxyapatite should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Breast-feeding

It is not known whether hydroxyapatite is excreted in human milk. Caution should be exercised when hydroxyapatite is administered to a nursing woman.

Storage

Store in a cool, dry place, away from direct sunlight. Keep out of reach of children.